Evidence map›Paper›PMID 41654985›Full record

ArticleBMC research notes2026

The utility of urine lipoarabinomannan as a tuberculosis treatment monitoring tool in people living with HIV.

Brian Otaalo, Joseph Musaazi, Ruth Nabisere-Arinaitwe, Shakira Babirye, Derek J Sloan, Willy Ssengooba, Lydia Nakiyingi, Steven J Reynolds, Barbara Castelnuovo, Yukari C Manabe and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brian OtaaloMakerere University Infectious Diseases Institute, Kampala, Uganda. otaalobrian@gmail.com.
Joseph MusaaziMakerere University Infectious Diseases Institute, Kampala, Uganda.
Ruth Nabisere-ArinaitweMakerere University Infectious Diseases Institute, Kampala, Uganda.
Shakira BabiryeInfectious Diseases Research Collaboration, Kampala, Uganda.
Derek J SloanUniversity of St Andrews, St. Andrews, UK.
Willy SsengoobaMakerere University College of Health Sciences, Kampala, Uganda.
Lydia NakiyingiMakerere University Infectious Diseases Institute, Kampala, Uganda.
Steven J ReynoldsNational Institute of Allergy and Infectious Diseases Division of Intramural Research, Bethesda, USA.
Barbara CastelnuovoMakerere University Infectious Diseases Institute, Kampala, Uganda.
Yukari C ManabeMakerere University Infectious Diseases Institute, Kampala, Uganda.
Christine Sekaggya-WiltshireMakerere University Infectious Diseases Institute, Kampala, Uganda.

Funding

TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Matthew Hamill · 2007 to 2026
$34.6M
NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
HIV Co-infections in Uganda: TB, Cryptococcus, and Viral Hepatitis.D43TW009771 · FIC · JOHNS HOPKINS UNIVERSITY · PI CASTELNUOVO, BARBARA, KAMBUGU, ANDREW DDUNGU · 2014 to 2023
$3.3M
European and Developing Countries Clinical Trials Partnership TMA2016CDF-1580FIC NIH HHS D43 TW009771FIC NIH HHS D43TW010132NIBIB NIH HHS U54 EB007958
6 · The paper itself

Abstract

objectiveThis pilot study aimed to evaluate whether urine lipoarabinomannan (LAM) testing can be used to monitor tuberculosis treatment response in people living with HIV.

resultsSeventy-five participants were enrolled, of whom 51 (68%) were women, and 43 (57.4%) were antiretroviral therapy naïve. CD4 cell counts were available for 49 participants with a median of 58 cells/mm

Indexed as

Antitubercular AgentsHIV InfectionsLipopolysaccharidesTuberculosisAdultCD4 Lymphocyte CountFemaleHumansMaleMiddle AgedPilot ProjectsAntitubercular AgentslipoarabinomannanLipopolysaccharidesHIVTuberculosisUrine lipoarabinomannan

Identifiers

PMID41654985
PMCPMC12977948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.