ArticleBMC ophthalmology2026
Clinical outcomes of autologous labial mucosal grafting for cicatricial entropion.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the efficacy and safety of autologous labial mucosal grafting for cicatricial entropion, with emphasis on visual outcomes, eyelid correction, symblepharon severity, and complications.
methodsA retrospective analysis was performed on 29 patients (38 eyes) who underwent autologous labial mucosal grafting between March 2019 and January 2025. Preoperative and postoperative best-corrected visual acuity, eyelid position (graded 0–4), symblepharon severity (graded 0–3), and complications were compared.
resultsAll surgeries were completed without severe intraoperative or postoperative complications, and grafts survived well without contraction or necrosis. Overall, best-corrected visual acuity showed no significant change after surgery (P = 0.545). By etiology, the burn-induced group showed a nonsignificant trend toward improvement, whereas the immune-mediated group remained stable. Both entropion and symblepharon scores improved significantly postoperatively (P < 0.05). Subgroup analysis showed greater benefits in burn-related cases compared with immune-mediated etiologies, particularly after a single procedure (P < 0.01). Multiple surgeries conferred no additional benefit. Patients with longer disease duration (≥ 40 months) tended toward better entropion correction, though this did not reach statistical significance (P = 0.097).
conclusionsAutologous labial mucosal grafting effectively restores eyelid structure and function in moderate to severe cicatricial entropion, especially after chemical or thermal burns. With low complication and recurrence rates, it is a safe and reliable option. Larger prospective studies are warranted to confirm long-term outcomes.
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