Evidence map›Paper›PMID 41654324›Full record

ArticleThe Laryngoscope2026

Clinical Features and Dental Pathologies in Maxillary Sinus Fungal Balls and Odontogenic Sinusitis.

Eunice Im, Lane Donaldson, Avraham Adelman, Nithin D Adappa, Yi-Wei Chen, Nikita Chapurin, Jennifer E Douglas, Glen E D'Souza, Jacob Eide, Maria Espinosa and 23 more

Abstract readMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Eunice ImMichigan State University College of Human Medicine, Grand Rapids, Michigan, USA.ORCID 0009-0004-0757-7790
Lane DonaldsonDepartment of Otolaryngology-Head and Neck Surgery, Henry Ford Health, Detroit, Michigan, USA.
Avraham AdelmanDepartment of Otolaryngology-Head and Neck Surgery, University of Florida, Gainesville, Florida, USA.
Nithin D AdappaDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yi-Wei ChenDivision of Rhinology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Nikita ChapurinDepartment of Otolaryngology-Head and Neck Surgery, University of Florida, Gainesville, Florida, USA.
Jennifer E DouglasDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3634-2067
Glen E D'SouzaDepartment of Otolaryngology-Head and Neck Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Jacob EideDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Maria EspinosaDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4290-2470
Chia-Hsiang FuDivision of Rhinology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Meha G FoxDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-1393-4174
Rohit GargDepartment of Otolaryngology-Head and Neck Surgery, Kaiser Permanente Orange County, Anaheim, California, USA.
Edward C KuanDepartment of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, USA.
Michael A KohanskiDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Marta KwiatkowskaDepartment of Otolaryngology and Laryngological Oncology, Military Institute of Medicine-National Research Institute, Warsaw, Poland.
Kevin LiDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
Derek H LiuDepartment of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, USA.
Tran Bao LockeDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-3838-3890
Chih-Feng LinDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Chadi MakaryDepartment of Otolaryngology-Head and Neck Surgery, West Virginia University, Morgantown, West Virginia, USA.ORCID 0000-0001-9967-4045
Alice OttaviDepartment of Health Sciences, San Paolo and Carlo Hospital, Otolaryngology Unit, University of Milan, Milan, Italy.
Peter PapagiannopoulosDepartment of Otolaryngology-Head and Neck Surgery, Rush University Medical Center, Chicago, Illinois, USA.
James N PalmerDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Charles C L TongDepartment of Otolaryngology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, New York, USA.
Bobby A TajudeenDepartment of Otolaryngology-Head and Neck Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Sanjena VenkateshDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0009-4051-9994
Kimberly WeiDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Frederick YooDepartment of Otolaryngology-Head and Neck Surgery, Kaiser Permanente Orange County, Anaheim, California, USA.
Alison J YuDivision of Rhinology and Skull Base Surgery, Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jun JinDepartment of Public Health Sciences, Henry Ford Health System, Detroit, Michigan, USA.
Alberto M SaibeneDepartment of Health Sciences, San Paolo and Carlo Hospital, Otolaryngology Unit, University of Milan, Milan, Italy.
John R CraigDepartment of Otolaryngology-Head and Neck Surgery, Henry Ford Health, Detroit, Michigan, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWhile maxillary sinus fungal balls (MSFB) can be associated with odontogenic conditions (MSFBO), MSFBO clinical and dental features have not been compared to odontogenic sinusitis (ODS). This multicenter study aimed to compare characteristics of MSFB, MSFBO, and ODS.

methodsA multicenter international retrospective cohort study was conducted on adults with MSFBs and ODS who underwent sinus surgery. First in MSFBs, it was determined whether different dental conditions were more likely in FB versus non-FB sides. Second, clinical features and dental pathologies were compared between MSFBO and ODS. For analyses, dental conditions were considered individually and as two groups: infectious pathologies and dental/oral procedures with indwelling metallic materials.

resultsAfter exclusions, there were 203 MSFBs and 163 ODS. Among MSFBs, 141 were MSFBOs. FB sides were associated with sinus protrusion of root canal treatment (RCT) materials (p = 0.040) and dental implants (p = 0.040). Compared to MSFBO, ODS patients were younger, more likely to have MS purulence (OR = 40.9, p < 0.010), more likely associated with apical periodontitis (OR = 2.59, p = 0.010) and oroantral fistulas (OR = 6.94, p = 0.020), and less likely associated with extruded RCT materials (OR = 0.01, p = 0.010) and protruded midface screws (OR < 0.01, p = 0.010). Comparing purulent MSFBO and ODS, ODS was more associated with infectious dental pathologies (p < 0.009).

conclusionCompared to MSFBs, MSFBOs were associated with RCT extrusion and implant protrusion. Compared to MSFBOs, ODS was more likely purulent and associated with infectious dental pathologies. While ODS is often distinct from MSFBO, the two conditions can coexist, and surgeons must determine whether patients have infectious dental pathology requiring treatment with both conditions. LEVEL OF EVIDENCE: 4:

Indexed as

Maxillary SinusMaxillary SinusitisMycosesRhinosinusitisAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studiesapical periodontitisdental implantendoscopic sinus surgeryfungal ballodontogenic sinusitisoroantral fistularoot canal treatment

Identifiers

PMID41654324
PMCPMC13253162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.