Evidence map›Paper›PMID 41653867›Full record

ArticleJournal of critical care2026

Dipeptidyl peptidase-3 to predict respiratory outcomes in patients hospitalized with COVID-19: A secondary analysis of a multicenter randomized trial.

J Pedro Teixeira, Christopher L Schaich, Caitlin C Ten Lohuis, Nathan D Nielsen, Peter Chen, Adit A Ginde, David N Hager, Akram Khan, Lisa H Merck, Basmah Safdar and 7 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

J Pedro TeixeiraDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA; Division of Nephrology, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA. Electronic address: jteixeira@salud.unm.edu.
Christopher L SchaichHypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Caitlin C Ten LohuisEmory Critical Care Center, Emory Healthcare, Atlanta, GA, USA.
Nathan D NielsenDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA; Section of Transfusion Medicine and Therapeutic Pathology, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Peter ChenWomen's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Adit A GindeDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
David N HagerDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Akram KhanDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Oregon Health and Science University, Portland, OR, USA.
Lisa H MerckDepartment of Emergency Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Basmah SafdarDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.
Jeffrey M SturekDivision of Pulmonary and Critical Care, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.
Marjolein de WitDepartment of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Michelle S HarkinsDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Wesley H SelfDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Sean P CollinsDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Laurence W BusseEmory Critical Care Center, Emory Healthcare, Atlanta, GA, USA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, GA, USA.
ACTIV-4 Host Tissue Investigators

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Oxidation-Specific Epitope IgA in Pulmonary FibrosisR01HL179312 · NHLBI · UNIVERSITY OF VIRGINIA · PI Jeffrey Michael Sturek · 2025 to 2026
$1.6M
Cardiac Autonomic Function, Cognitive Performance, and Neurocognitive OutcomesK01AG073581 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SCHAICH, CHRISTOPHER · 2021 to 2024
$384k
NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS R01 HL179312NIA NIH HHS K01 AG073581
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute lung injuryAcute respiratory failureARDSCOVID-19Dipeptidyl peptidase-3DPP3HypoxemiaRenin-angiotensin-aldosterone systemViral pneumonia

Identifiers

PMID41653867
PMCPMC13012293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.