Evidence map›Paper›PMID 41653836›Full record

Trial reportInternational dental journal2026

Clinical, Immunological and Microbiological Improvements With Zinc-Coated Healing Abutments During the Healing Phase.

Yu Zhu, Shu-Li Liu, Xiong Lu, Gang Luo, Zuo-Hui Xiao, Ying-Kai Wang, Jie Zhou, Shi-Chong Qiao

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu ZhuNational Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China; Department of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shu-Li LiuNational Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China; Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiong LuInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Gang LuoInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Zuo-Hui XiaoNational Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China; Department of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ying-Kai WangNational Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China; Department of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jie ZhouInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China. Electronic address: zhoujie@swjtu.edu.cn.
Shi-Chong QiaoNational Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China; Department of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: Shichong83@sjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the clinical, immunological, and microbiological effects of zinc-coated healing abutments (Zn-TiO

methodsThe study was a prospective, non-randomised, single-centre, open-label, proof-of-concept clinical trial. The Ti and Zn-TiO

resultsEleven patients with 22 implants attended the 8-week examination. The BOP% was significantly lower in the Zn-TiO

conclusionWithin the limitations of the study, the zinc-coated healing abutments improved early peri-implant soft tissue health clinically and immunologically. However, further studies are still needed to exclude the interference of soft tissue phenotype and confirm the relationship between microbial and clinical findings.

Indexed as

Dental AbutmentsWound HealingZincDental Implant-Abutment DesignDental ImplantsFemaleGingival Crevicular FluidHumansInterleukin-6MaleMiddle AgedProspective StudiesTitaniumTumor Necrosis Factor-alphaDental ImplantsInterleukin-6Titaniumtitanium dioxideTumor Necrosis Factor-alphaZincClinical outcomesImplant healing abutmentsMicrobiomePro-inflammatory cytokinesZinc coatings

Identifiers

PMID41653836
PMCPMC12907655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.