Evidence map›Paper›PMID 41653382›Full record

ArticleVirus genes2026

Generation of an infectious cDNA clone of BJ-Swzp-2022, a Group III Isolate of Getah Virus.

Dongni Kong, Liang Meng, Dan Liu, Jia Wang, Xiaojie Huang, Tianshu Zhai, Yong Deng, Qi Xue, Hongju Wu, Yaqing Mao and 2 more

Abstract read
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In one paragraph

Article in Virus genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dongni KongChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Liang MengState Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, 150069, China.
Dan LiuChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Jia WangChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Xiaojie HuangChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Tianshu ZhaiChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Yong DengChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Qi XueChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Hongju WuChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Yaqing MaoChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China.
Haiwei WangState Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, 150069, China. wanghaiwei@caas.cn.
Huawei WuChina Institute of Veterinary Drug Control, No. 8 Nandajie, Zhongguancun, Haidian, Beijing, 100081, China. whw101@21cn.com.

Funding

National Key Research and Development Program of China 2022YFD1800604
6 · The paper itself

Abstract

Getah virus (GETV), a mosquito-borne arbovirus, possesses many susceptible hosts, including pigs, horses, cattle, and blue foxes. Currently, the biological characteristics and pathogenic mechanisms of GETV remain to be investigated. A GETV, isolated from a contaminated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) live vaccine, was designated as BJ-Swzp-2022. Subsequently, the complete genome of the GETV BJ-Swzp-2022 was sequenced to construct a full-length infectious cDNA clone using T7 RNA polymerase. Transfection of BSR T7/5 cells expressing T7 RNA polymerase with this infectious clone resulted in the rescue of GETV, which exhibited replication and replication characteristics similar to those of the parental virus. Establishing this platform would facilitate understanding the pathogenic mechanisms of GETV and developing novel vaccines.

Indexed as

AlphavirusDNA, ComplementaryAnimalsCell LineCloning, MolecularGenome, ViralPorcine respiratory and reproductive syndrome virusSwineVirus ReplicationDNA, ComplementaryGetah virusInfectious clonePlaque assayVirus isolation

Identifiers

PMID41653382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.