Evidence map›Paper›PMID 41653278›Full record

ArticleJournal of robotic surgery2026

Preoperative Iron Isomaltoside administration enhances postoperative anemia recovery in robotic pancreatic surgery.

Tianyu Li, Yutong Zhao, Liangbo Dong, Jiashu Han, Bangbo Zhao, Chen Lin, Weibin Wang

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07551375 recruitingnot on this map

Fast Abdominopelvic MRI With Deep Learning-Based Reconstruction Algorithm: Image Quality Evaluation and Application in Patients With Common Abdominal and Pelvic Diseases

TypeobservationalSponsorPeking Union Medical College HospitalRan2024 to 2026Enrolled300ConditionsAcute Cholecystitis
NCT07551388 nacompletednot on this map

Optimal Weight-Based Indocyanine Green Dosage for Fluorescent Cholangiography in Laparoscopic Cholecystectomy Among Chinese Population:Construction and Validation

TypeinterventionalSponsorPeking Union Medical College HospitalRan2025 to 2025Enrolled21ConditionsAcute CholecystitisArmsIndocyanine Green (ICG) Fluorescence Cholangiography
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianyu Li *Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yutong Zhao *Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liangbo DongDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jiashu HanDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bangbo ZhaoDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen LinDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. linchen0818@sina.com.
Weibin WangDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. wwb_xh@163.com.

Funding

National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases ZK12101National Natural Science Foundation of China 82173074
6 · The paper itself

Abstract

Anemia is prevalent among surgical patients, particularly in those undergoing pancreatic surgery, and is associated with increased morbidity and mortality. Iron isomaltoside (IIM), a novel intravenous iron formulation, has demonstrated efficacy in correcting anemia with lower risk of side effects. This study aims to evaluate the efficacy of IIM in managing perioperative anemia in patients undergoing robotic pancreatic surgery. Our study included 90 consecutive patients underwent robotic pancreatic surgery at Peking Union Medical College Hospital (PUMCH) from June 2023 to June 2024. After exclusion, a total of 84 patients were categorized into a control group (n = 70) and an IIM group (n = 14). Baseline characteristics, surgical outcomes, and hemoglobin levels were compared. Propensity score matching (PSM) was used to adjust for baseline differences. Hemoglobin concentrations were assessed before surgery and on postoperative days (POD) 1, 3, 7, and 30. Preoperative hemoglobin were significantly lower in IIM group (115.86 ± 22.76 g/L) compared to control group (132.69 ± 13.96 g/L, p = 0.018). Postoperatively, hemoglobin levels declined in both groups, reaching their lowest on POD 1, and gradually increased thereafter. By POD30, the hemoglobin levels of patients in IIM group had caught up with control group (119.36 ± 9.04 vs. 120.11 ± 12.27 g/L, p = 0.827). The changes in hemoglobin levels (Δ) demonstrated significant improvements in the IIM group. At POD1, the decrease in hemoglobin was significantly smaller in the IIM group compared to the control group (ΔPOD1: -3.93 ± 13.79 vs. -15.41 ± 12.50, P = 0.003). Similar trends were observed at POD7 (ΔPOD7: -6.14 ± 19.42 vs. -18.47 ± 12.12, P = 0.037) and at POD30, where the IIM group showed an increase in hemoglobin levels compared to a decrease in the control group (ΔPOD30: 3.50 ± 19.78 vs. -12.57 ± 12.67, P = 0.010). After PSM to account for differences in baseline characteristics, the changes in hemoglobin levels (Δ) postoperatively continued to show significant improvements in the IIM group. Surgical outcomes, including operative time, blood loss, transfusion rates, and postoperative complications, were comparable between these two groups before and after PSM. There were no side effects due to the administration of intravenous IIM. IIM could effectively improve postoperative hemoglobin levels in patients undergoing robotic pancreatic surgery.

Indexed as

AnemiaDisaccharidesFerric CompoundsPancreasPancreatectomyPostoperative ComplicationsPreoperative CareRobotic Surgical ProceduresAgedFemaleHemoglobinsHumansMaleMiddle AgedDisaccharidesFerric CompoundsHemoglobinsiron isomaltoside 1000HemoglobinIron isomaltosidePerioperative anemiaRobotic pancreatic surgerySurgical outcomes

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.