Evidence map›Paper›PMID 41653239›Full record

ArticleJournal of fluorescence2026

Chiral Ratiometric Fluorescent Silicon Nanoparticles for "Turn-on" Enantioselective Recognition of Tryptophan.

Chen Liu, Yaning Duan, Cancan Lu, Yu Fu, Cuiling Ren, Hongli Chen

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Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chen Liu *State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Yaning Duan *State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Cancan LuState Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Yu FuState Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Cuiling RenState Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China. rencl@lzu.edu.cn.
Hongli ChenState Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a novel ratiometric fluorescent silicon nanoparticles (LSiNPs) system for enantioselective recognition of tryptophan. The LSiNPs were synthesized by DAMO, rhodamine B and chiral ligand L-Lys via a one-pot method at room temperature. Upon increasing L-Trp concentration, the fluorescence intensity of the system at 440 nm progressively enhanced while maintaining stability at 575 nm, whereas D-Trp showed negligible effects. The sensor demonstrated an enantioselectivity coefficient of 11.7, enabling quantitative detection of L-Trp and determining enantiomeric composition in racemic mixtures. LSiNPs exhibits good selectivity towards L-Trp among 13 typical amino acid enantiomers. It can be applied to detect L-Trp in L-Tryptophan capsules rapidly and accurately. The recognition mechanism of tryptophan enantiomers was studied, indicating that the modification of chiral ligand L-Lys plays an important role in the recognition process. This work establishes a “turn-on” ratiometric strategy for chiral recognition of tryptophan enantiomers, offering new perspectives for enantiomer differentiation.

Indexed as

Chiral discriminationFluorescent silicon nanoparticleRatiometric fluorescent probeTryptophan enantiomer

Identifiers

PMID41653239

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