Evidence map›Paper›PMID 41653167›Full record

Trial reportJournal of nutrition education and behavior2026

Mechanisms of Strong Hearts, Healthy Communities-2.0 Effects on Weight: A Mediation Analysis.

Chad D Rethorst, Margaret Demment, Meredith L Graham, Seungyeon Ha, Alexandra L MacMillan Uribe, Brian K Lo, Jacob Szeszulski, Phrashiah Githinji, David Strogatz, Sara C Folta and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nutrition education and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chad D RethorstInstitute for Advancing Health through Agriculture, Texas A&M Agrilife Research, Dallas, TX; Texas A&M Agrilife Research Center - Dallas, Dallas, TX; Departmenent of Nutrition, Texas A&M University, College Station, TX. Electronic address: chad.rethorst@ag.tamu.edu.
Margaret DemmentInstitute for Advancing Health through Agriculture, Texas A&M Agrilife Research, Dallas, TX.
Meredith L GrahamInstitute for Advancing Health through Agriculture, Texas A&M Agrilife Research, Dallas, TX.
Seungyeon HaStatistical Consultation Center, Texas A&M University, College Station, TX.
Alexandra L MacMillan UribeInstitute for Advancing Health through Agriculture, Texas A&M Agrilife Research, Dallas, TX; Texas A&M Agrilife Research Center - Dallas, Dallas, TX; Departmenent of Nutrition, Texas A&M University, College Station, TX.
Brian K LoDepartment of Family Relations and Applied Nutrition, University of Guelph, Guelph, Ontario, Canada.
Jacob SzeszulskiInstitute for Advancing Health through Agriculture, Texas A&M Agrilife Research, Dallas, TX; Texas A&M Agrilife Research Center - Dallas, Dallas, TX; Departmenent of Nutrition, Texas A&M University, College Station, TX.
Phrashiah GithinjiDepartment of Health & Kinesioglogy, University of Utah, Salt Lake City, UT.
David StrogatzBassett Research Institute, Cooperstown, NY.
Sara C FoltaFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA.
Miriam E NelsonFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA.
Rebecca A Seguin-FowlerInstitute for Advancing Health through Agriculture, Texas A&M AgriLife Research, College Station, TX; Departmenent of Nutrition, Texas A&M University, College Station, TX.

Funding

Strong Hearts_Healthy Communities_A Rural Community CVD Prevention ProgramR01HL120702 · NHLBI · CORNELL UNIVERSITY · PI SEGUIN-FOWLER, REBECCA ANNE · 2014 to 2017
$1.6M
NHLBI NIH HHS R01 HL120702
6 · The paper itself

Abstract

objectiveTo evaluate potential mediators of weight loss in the Strong Hearts, Health Communities-2.0 (SHHC-2.0) trial.

designCommunity-randomized trial (intervention vs delayed intervention). Outcomes were evaluated at baseline and postintervention.

settingEleven rural, medically-underserved communities

participantsWomen (n = 182), mean age 57.2 years, 97.6% White, non-Hispanic.

interventionClasses delivered 2 times/wk for 24 weeks, targeting diet and physical activity behaviors. MAIN OUTCOMES MEASURES: Dependent variable: weight; mediators: diet and physical activity behaviors, and related psychosocial factors. ANALYSIS: Mixed linear regressions evaluated the effect of mediators on weight loss.

resultsSignificant mediators included dietary behaviors (Rapid Eating Assessment for Participants-Short; 31.8%; P = 0.03), healthy eating attitudes (23.0%; P = 0.03), and dietary cognitive restraint (29.8%; P = 0.01). Physical activity did not mediate weight loss; however, a worsening in attitudes toward exercise was a mediator of weight loss (22.6%; P = 0.01). Social support for diet and physical activity was unchanged in the intervention group and did not mediate weight loss effects. CONCLUSIONS AND IMPLICATIONS: Healthy eating attitudes and dietary cognitive restraint represent important targets for future behavioral interventions for weight loss. Hypothesized mediators found to be nonsignificant (i.e., social support) represent opportunities for future intervention optimization.

Indexed as

ExerciseHealth BehaviorHealth PromotionWeight LossAgedFeeding BehaviorFemaleHumansMediation AnalysisMiddle AgedRural Populationeating behaviorinterventionnutritionphysical activitywomen

Identifiers

PMID41653167
PMCPMC13292833

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.