Evidence map›Paper›PMID 41653041›Full record

SynthesisJournal of renal care2026

Social Isolation and Loneliness in People Living With Chronic Kidney Disease and Kidney Failure: A Mixed Method Systematic Review.

Amanda L McKie, Paul J Buttel

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of renal care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amanda L McKieUniversity of Canberra, Canberra, Australian Capital Territory, Australia.ORCID https://orcid.org/0000-0002-4180-7463
Paul J ButtelDepartment of Health, Disability and Ageing, Canberra, Australian Capital Territory, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople living with chronic kidney disease and kidney failure experience a wide range of challenging burdens, as many try to manage their condition effectively. Social isolation and loneliness are commonly associated with chronic kidney disease and kidney failure, and the restrictions of their disease make establishing social connections difficult. The impact of social isolation and loneliness can negatively affect a person's health and wellbeing in many ways.

objectiveTo conduct a mixed method systematic review of studies about social isolation and loneliness in people with chronic kidney disease and kidney failure.

designUsing the PRISMA guidelines, six databases (Medline, CINAHL, Cochrane Library, PsycINFO, Scopus and Google Scholar) were comprehensively searched using keywords from June 2005 to August 2025. Studies were quality assessed.

resultsSeven studies met the eligibility criteria (two quantitative and five qualitative research design). Four common factors emerged from the review of studies that included: coping, support, psychological outcomes and impacts that affect everyday life and daily routine.

conclusionSocial isolation and loneliness impact people living with chronic kidney disease and kidney failure in many ways across all areas of their lives. Negative emotions arose that made people question the point of continuing treatment as others experienced elevated levels of anxiety and depression associated with social isolation and loneliness. Support services and early interventions need to be considered to better manage social isolation and loneliness for people living with this chronic health condition.

Indexed as

LonelinessRenal Insufficiency, ChronicSocial IsolationAdaptation, PsychologicalHumansKidney Failure, ChronicQualitative ResearchSocial Supportchronic kidney diseasekidney failurelonelinesssocial isolationsystematic review

Identifiers

PMID41653041
PMCPMC12882110

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.