Evidence map›Paper›PMID 41652956›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2026

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging-Guided Diagnosis and Therapy.

Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zekun YanJoint Key Laboratory of Ministry of Education, Institute of Applied Physics and Materials Engineering (IAPME), University of Macau, Macau SAR, China.
Yupeng LiuJoint Key Laboratory of Ministry of Education, Institute of Applied Physics and Materials Engineering (IAPME), University of Macau, Macau SAR, China.ORCID https://orcid.org/0000-0003-1839-7037
Jinyun TanHuashan Hospital, Fudan University, Shanghai, China.
Songnan QuJoint Key Laboratory of Ministry of Education, Institute of Applied Physics and Materials Engineering (IAPME), University of Macau, Macau SAR, China.ORCID https://orcid.org/0000-0003-4159-096X

Funding

National Natural Science Foundation of China 52502204Research Grant from the University of Macau MYRG-CRG2025-00011-FHSResearch Grant from the University of Macau MYRG-GRG2025-00148-IAPMEScience and Technology Development Fund of Macau SAR 0002/2024/TFPScience and Technology Development Fund of Macau SAR 0139/2022/A3UM Postdoctoral Fellowship Class A
6 · The paper itself

Abstract

Carbon dots (CDs) have emerged as a transformative class of luminescent nanomaterials for biomedical applications, offering superior biocompatibility, photostability, and tunability compared to conventional organic dyes and inorganic quantum dots. This review distinguishes itself by establishing a critical "Structure-Property-Application" feedback framework. We comprehensively summarize the rational design of CDs, specifically elucidating how core size, surface chemistry, and heteroatom doping can be precisely engineered to tailor optical emission into the near-infrared II window. Furthermore, the versatile roles of CDs in cancer theranostics are critically discussed, encompassing their utility in subcellular tracking, image-guided surgery, and multifunctional therapeutic platforms such as photothermal therapy (PTT), photodynamic therapy (PDT), and targeted drug delivery. Finally, we address the current challenges regarding scalability, reproducibility, and biosafety, providing a perspective on the future roadmap for the clinical translation of high-performance CD-based agents.

Indexed as

CarbonCarbon Quantum DotsNeoplasmsQuantum DotsTheranostic NanomedicineAnimalsDrug Delivery SystemsHumansLuminescencePhotochemotherapyPhotothermal TherapyCarbonbioimagingcancer theranosticscarbon dotsdiagnosistherapy

Identifiers

PMID41652956
PMCPMC13472343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.