Evidence map›Paper›PMID 41652853›Full record

ArticlePlant biotechnology journal2026

An Elite Haplotype of Nitrogen-Use-Efficiency Gene LHT5 Enhances Salt Tolerance in Rice.

Saisai Wang, Xingzhou Jiang, Gaoming Chen, Wei Wu, Chen Xu, Mingyu Du, Shuji Xiang, Xinran Cheng, Yunlu Tian, Junjie Tan and 2 more

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. aBIOTECH · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saisai WangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Xingzhou JiangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Gaoming ChenState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.ORCID https://orcid.org/0000-0002-1010-6461
Wei WuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Chen XuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Mingyu DuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Shuji XiangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Xinran ChengState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Yunlu TianState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Junjie TanState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.
Chunming WangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.ORCID https://orcid.org/0000-0003-3780-8065
Jianmin WanState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Jiangsu Zhongshan Biological Breeding Laboratory, Nanjing, China.ORCID https://orcid.org/0000-0002-0017-8760

Funding

China Postdoctoral Science Foundation 2023M741753Foundation of Biological Breeding Zhongshan Lab ZSBBL-KY2024-01Jiangsu Funding Program for Excellent and Postdoctoral Talent 2022ZB351Jiangsu Funding Program for Excellent and Postdoctoral Talent 2023ZB492National Key Research and Development Project 2022YFD1201702National Natural Science Foundation of China 32401844Natural Science Foundation of Jiangsu Province BK20220997Natural Science Foundation of Jiangsu Province BK20230982Scientific Innovation 2030 Project 2022ZD0401703
6 · The paper itself

Abstract

Amino acids serve as fundamental building blocks and signalling molecules in plants, orchestrating stress adaptation mechanisms against diverse biotic and abiotic environmental challenges. However, the mechanism by which plants alter their nutrient metabolism processes to coordinate nitrogen use efficiency (NUE) and salt tolerance remains elusive. Here, we identified a Lysine-Histidine-type transporter 5 (LHT5) gene through genome-wide association studies (GWAS) that enhances NUE via amino acid accumulation regulation. Further research showed that OsLHT5 also confers salt tolerance in rice by promoting proline biosynthesis through transcriptional upregulation of OsP5CS1 and OsP5CS2 genes, thereby increasing cellular proline levels for osmotic adjustment. Notably, we identified a functionally critical 30-bp deletion in the OsLHT5 coding region, designated as the elite haplotype LHT5

Indexed as

HaplotypesNitrogenOryzaPlant ProteinsSalt ToleranceGene Expression Regulation, PlantGenes, PlantGenome-Wide Association StudyPlants, Genetically ModifiedProlineNitrogenPlant ProteinsProlinelysine‐histidine‐type transporternitrogen use efficiencyOryza sativa L.salt tolerancesuperior allele

Identifiers

PMID41652853
PMCPMC13205599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.