ArticleBMC infectious diseases2026
Evaluating the predictive power of lactate-to-albumin ratio on 30-day mortality among sepsis patients: a retrospective cohort study.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Association between lactate to albumin ratio and 28-day all-cause mortality in patients with extracorporeal membrane oxygenation: a retrospective multi-cohort study.BMC cardiovascular disorders · 2026Article
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7 authors.
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Abstract
backgroundThe lactate-to-albumin ratio (LAR) is a predictor in sepsis that has been shown to outperform lactate and albumin. However, the role of LAR and mortality in Chinese adult patients with sepsis has not been evaluated.
methodsThis retrospective study aims to probe into the predictive value of the LAR for 30-day mortality in Chinese adult patients with sepsis, comparing its effectiveness to traditional markers such as lactate and albumin. This retrospective cohort study utilized data from Dr. Wang’s study published in PLOS ONE. This data was Dongyang People’s Hospital admitting to the emergency department between June 2013 and September 2021.
resultsAmong the 1,205 sepsis patients, 1,014 survived, and 191 did not, yielding a 30-day mortality rate of 15.9%. Uni- and multivariate logistics regression model were used. Meanwhile, Receiver Operating Characteristic (ROC) analysis was used to assess the predictive ability of lactate, albumin, and LAR for 30-day mortality. Multivariable logistic regression analysis confirmed that each 1-unit increase in LAR corresponded to a 97% increase in the risk of 30-day mortality, with an odds ratio (OR) of 1.97 (95% confidence interval (CI) 1.67–2.33, P < 0.001). Meanwhile, the area under the ROC curve (AUC) of LAR 77.68% was obviously superior to albumin 63.72% and lactate 76.32%.
conclusionsThe findings uncover a notable correlation between higher LAR levels and increased 30-day mortality risk in Chinese adult patients with sepsis. CLINICAL TRIAL NUMBER: Not applicable.
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