Evidence map›Paper›PMID 41652413›Full record

Trial reportBMC ophthalmology2026

Application of directional customized corneal relaxing incision in EVO ICL implantation: high myopia with low astigmatism.

Guanghan Xu, Mingrui Cheng, Qingyang Liu, Mingwei Li, Shumin Tang, Boliang Li, Yinjie Jiang, Yadi Lei, I-Chun Lin, Zhiwei Mao and 2 more

Abstract readClinical Trial
In one paragraph

Trial report in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guanghan Xu *Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Mingrui Cheng *Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Qingyang Liu *Department of ophthalmology, Dongguan People's Hospital, Dongguan, China.
Mingwei LiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Shumin TangDepartment of Ophthalmology, Binhai Campus of the First Affiliated Hospital, National Regional Medical Center, Fujian Medical University, Fuzhou, China.
Boliang LiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Yinjie JiangFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Yadi LeiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
I-Chun LinFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Zhiwei MaoFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Xun ChenFudan University Eye Ear Nose and Throat Hospital, Shanghai, China. chenxun19910923@163.com.
Xiaoying WangFudan University Eye Ear Nose and Throat Hospital, Shanghai, China. doctxiaoyingwang@163.com.

Funding

National Natural Science Foundation of China 82171095Project of Shanghai Science and Technology 19140900700
6 · The paper itself

Abstract

purposeTo evaluate the efficacy of EVO-ICL implantation combined with a corneal relaxing incision for the correction of moderate to high myopia with low astigmatism.

designProspective non-randomized clinical trial.

methodsThis study included 35 eyes of 35 patients with astigmatism corrected by corneal relaxing incision (CRI) on the steep meridian and 30 eyes of 30 patients who underwent conventional temporal incision as controls. Visual acuity, refractive parameters, keratometry, corneal astigmatism, and corneal aberration were measured preoperatively and 1 and 3 months postoperatively.

resultsThe refractive astigmatism of the CRI group decreased significantly from 0.89 ± 0.22 preoperatively to 0.39 ± 0.25 D at 1 month and 0.35 ± 0.30 D at 3 months postoperatively, and from 0.46 ± 0.32 D to 0.45 ± 0.34 D and 0.44 ± 0.30 D in the control group, respectively (P < 0.001). The preoperative anterior corneal astigmatism of the CRI group was significantly higher than the control group (P < 0.001) and decreased significantly from 1.03 ± 0.32 D preoperatively to 0.74 ± 0.36 D at 1 month and 0.69 ± 0.39 D at 3 months postoperatively (P < 0.001). The preoperative posterior corneal astigmatism of the CRI group decreased significantly from 0.32 ± 0.11 D preoperatively to 0.28 ± 0.12 D at 1 month and 0.25 ± 0.10 D at 3 months postoperatively (P < 0.001). There were significant differences in the postoperative RMS of trefoil aberration and total HOAs of the whole cornea, anterior cornea, and posterior cornea between the two groups (P < 0.05).

conclusionEVO-ICL implantation combined with a corneal relaxing incision to correct moderate-to-high myopia with low astigmatism is safe and effective with good short-term stability.

Indexed as

AstigmatismCorneaLens Implantation, IntraocularMyopiaMyopia, DegenerativePhakic Intraocular LensesAdultCorneal TopographyFemaleHumansMaleProspective StudiesRefraction, OcularTreatment OutcomeVisual AcuityYoung Adult

Identifiers

PMID41652413
PMCPMC12973601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.