Evidence map›Paper›PMID 41652220›Full record

ArticleNature cancer2026

METTL3-based epitranscriptomic editing screening identifies functional m

Xin Xu, Yujuan Wang, Helen Zhu, Magnus Lam, Wenqin Luo, Mona Teng, Yin Liu, Wang Yuan Guo, Aastha Aastha, Xi Xu and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xin Xu *Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China. xinxu768@smu.edu.cn.ORCID http://orcid.org/0000-0003-4670-1243
Yujuan Wang *Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Helen Zhu *Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Magnus LamPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Wenqin LuoPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Mona TengPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Yin LiuDepartment of Laboratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Wang Yuan GuoPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Aastha AasthaPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Xi XuPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Sujun ChenPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-1941-3951
Xinpei CiPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Shiyan WangPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.
Yong ZengPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-5719-1272
Guanghui ZhuPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-1495-4238
Thomas KislingerPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-3525-5540
Mathieu LupienPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-0929-9478
Ming-Sound TsaoPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-9160-5405
Housheng Hansen HePrincess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada. Hansenhe@uhnresearch.ca.ORCID http://orcid.org/0000-0003-2898-3363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

AdenosineLung NeoplasmsMethyltransferasesProstatic NeoplasmsAnimalsCell Line, TumorCell ProliferationEpitranscriptomeEpitranscriptomicsGene Expression Regulation, NeoplasticHumansMaleMiceRNA-Binding ProteinsRNA MethylationAdenosineMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA-Binding ProteinsYTHDF1 protein, humanYTHDF3 protein, human

Identifiers

PMID41652220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.