A Bright and Dynamic Future in Structural Biology.

Xiaojing Yang

Abstract readReview

In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Xiaojing YangDepartment of Chemistry, University of Illinois Chicago, Chicago, IL, USA. xiaojing@uic.edu.

Funding

Structures, Dynamics and Signaling Mechanisms of Modular PhotoreceptorsR01EY024363 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YANG, XIAOJING · 2014 to 2021

$2.9M

Structures, light signaling and allostery mechanisms of photoreceptor kinasesR01EY035671 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Xiaojing Yang · 2024 to 2026

$1.2M

NEI NIH HHS R01 EY024363NEI NIH HHS R01 EY035671

6 · The paper itself

Abstract

Structural biology has played a key role in revealing the molecular basis of life in the past 50 years. Thanks to several landmark technical advances, the field has made significant strides from determining static macromolecular structures at atomic resolution to observing functional dynamics of protein structures spanning a vast conformational space and beyond the crystal lattice. As innovations in structural biology continue to transform modern biology and medicine, this chapter presents a perspective on past triumphs, current challenges, and future directions with a focus on how to capture protein structure dynamics using experimental and analytical methods.

Indexed as

ProteinsAnimalsCryoelectron MicroscopyCrystallography, X-RayHumansModels, MolecularProtein ConformationProteinsCryo-electron microscopyCrystallographyFunctional structure dynamicsProtein structureResolution of structural heterogeneity

Identifiers

PMID41652167

DOI10.1007/978-3-032-07511-6_10

PMCPMC13162279

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.