Evidence map›Paper›PMID 41652149›Full record

Trial reportAcademic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry2026

Optimizing the Work of Learning for Flourishing: A Randomized Pilot Study of a Digital CBT-Based Intervention in Medical Students.

Justin S Sanchez, Demetrius Perry, Anna Kinghorn, David Vermette, Teddi Gray, Jennifer G Duncan, Brad Evanoff, Ginger E Nicol

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06914843 (A Randomized Controlled Pilot of a Web-based Intervention for Cognitive Behavioral Therapy-based Training to Improve Mental Health in Medical Trainees), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06914843 nacompletednot on this map

A Randomized Controlled Pilot of a Web-based Intervention for Cognitive Behavioral Therapy-based Training to Improve Mental Health in Medical Trainees

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2024Enrolled35ConditionsMental Health Wellness 1ArmsOptimalWork, Podcast Listening
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Justin S SanchezWashington University School of Medicine, St. Louis, MO, USA. j.s.sanchez@wustl.edu.ORCID http://orcid.org/0000-0003-4421-3078
Demetrius PerryWashington University School of Medicine, St. Louis, MO, USA.
Anna KinghornWashington University School of Medicine, St. Louis, MO, USA.
David VermetteWashington University School of Medicine, St. Louis, MO, USA.
Teddi GrayWashington University School of Medicine, St. Louis, MO, USA.
Jennifer G DuncanWashington University School of Medicine, St. Louis, MO, USA.
Brad EvanoffWashington University School of Medicine, St. Louis, MO, USA.
Ginger E NicolWashington University School of Medicine, St. Louis, MO, USA.

Funding

HRSA HHS U3M45389
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the feasibility, acceptability, and impact of a digital cognitive behavioral therapy (CBT)-based intervention to improve well-being in medical students.

methodsThe authors conducted a 16-week randomized (1:1) controlled trial of a digital CBT-based intervention (OptimalWork) compared to a podcast listening control in medical students. Both interventions were fully remote, self-paced, and designed to take 10-15 min per day, 5 days per week for 4 weeks. Primary outcomes were feasibility and acceptability; measures of impact included flourishing (Flourish Index) and burnout (Professional Fulfillment Index) at 8 weeks. Qualitative analysis of open-ended feedback and exit interviews was performed to understand participants' experience with the intervention, as well as barriers and facilitators of implementation.

resultsThirty-five medical students were enrolled and randomized. The OptimalWork group showed improvements in work engagement, burnout, anxiety, and stress, and an increase in overall flourishing. Dropout rates were high in both arms (46% by 4 weeks, 56% by 16 weeks), with lower baseline work engagement and higher stress predicting attrition. Qualitative analysis revealed that students who completed OptimalWork found it feasible, relevant, and helpful, while participants who dropped out cited time constraints and difficulty with daily habit formation.

conclusionsThis pilot study demonstrates the feasibility of delivering a CBT-based digital intervention designed to improve well-being at work for medical students and offers insights into barriers and facilitators that can guide implementation efforts.

trial registrationClinicalTrials.gov identifier: NCT06914843 (July 24, 2024, retrospectively registered).

Indexed as

Burnout, ProfessionalCognitive Behavioral TherapyStudents, MedicalAdultDigital MediaFeasibility StudiesFemaleHumansMalePilot ProjectsPsychological Well-BeingYoung AdultBurnoutCognitive behavioral therapyDigital mental healthFlourishingMedical students

Identifiers

PMID41652149
PMCPMC13588825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.