ReviewDigestive diseases and sciences2026
Gastrointestinal Bleeding in Severe Acute Pancreatitis: Pathogenesis and Clinical Management.
Review in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Severe acute pancreatitis (SAP) is associated with a broad spectrum of local and systemic complications, among which gastrointestinal bleeding (GIB), although relatively uncommon, confers a disproportionately high mortality risk. The underlying pathogenic mechanisms remain incompletely elucidated and are distinctly multifactorial, involving acute gastric mucosal lesions, stress-induced ulcers, esophageal and gastric varices, and pseudoaneurysm formation and rupture. This review aims to systematically synthesize current evidence on the pathogenesis of SAP-associated GIB, thereby informing the development of targeted intervention strategies, improving the precision of individualized therapeutic decision-making, and ultimately providing a robust theoretical basis to optimize patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.