Evidence map›Paper›PMID 41652024›Full record

ArticleAesthetic plastic surgery2026

Not Merely an Enveloping Membrane: Anatomy of the Preaponeurotic Fat Membrane and Its Role in Blepharoptosis Correction.

Hanxing Zhao, Ying Zhang, Wilson A Wijaya, Zhixing Chen, Fengqin Song, Wencheng Fan, Linghuan Zeng, Zhiwei Zhao, Zhenyu Zhang, Zhengyong Li

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

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10 authors.

Hanxing Zhao *Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Ying Zhang *Department of Ophthalmology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Wilson A WijayaDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Zhixing ChenDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Fengqin SongDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Wencheng FanDepartment of Medical Cosmetology, Sichuan Integrative Medicine Hospital, No. 51 Section 4, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Linghuan ZengDepartment of Medical Cosmetology, Sichuan Integrative Medicine Hospital, No. 51 Section 4, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Zhiwei ZhaoDepartment of Human Anatomy, West China School of Basic Medicine and Forensic Medicine, Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Zhenyu ZhangDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China.
Zhengyong LiDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610000, Sichuan Province, People's Republic of China. ZhengyongLi_WCH@163.com.

Funding

The "1,3,5" Project for Disciplines of Excelence, West China Hospital, Sichuan University ZYPY20003
6 · The paper itself

Abstract

backgroundIn blepharoplasty, a preaponeurotic fat pad has been considered to provide padding and structural support for the eyelid. In our practice, we have identified a dense fibrous membrane surrounding the preaponeurotic fat pad, which can transmit the uplift force of the levator muscle.

objectivesAs the preaponeurotic fat pad and its relationship with the surrounding layers remain controversial, this study aims to determine the histological characteristics of the preaponeurotic fat pad and to introduce a procedure involving the advancement of the posterior layer of the preaponeurotic fat membrane in blepharoptosis correction.

methodsThis retrospective study enrolled 42 eyes from 28 blepharoptosis patients who underwent a preaponeurotic fat membrane advancement procedure with or without levator aponeurotic advancement between October 2020 and June 2023. Six cadaveric upper eyelids from three fresh cadaver heads were harvested for histological examination, and one formalin-treated cadaver head was used for macroscopic anatomic evaluation.

resultsThe mean preoperative MRD1 was 1.89 ± 0.89 mm. Among the forty-two upper eyelids, thirty-six underwent advancement of the preaponeurotic fat membrane. The other six upper eyelids had inadequate correction after performing the levator aponeurosis advancement, and therefore, a combined preaponeurotic fat membrane advancement was performed. Nine patients reported lagophthalmos during the first three months postoperatively, but this condition significantly improved by six months postoperatively. In anatomic evaluation, multilayered fibrous tissue structures were identified in and around the preaponeurotic fat pad.

conclusionsBased on our clinical observations and anatomical studies, we believe that this fibrous envelope can be used to correct mild-to-moderate ptosis. The indications for this procedure range from mild-to-moderate ptosis. It can be used alone in patients with mild- or pseudo-ptosis due to overloading of the upper eyelid, or it can be used in conjunction with levator aponeurosis advancement in patients when the procedure is insufficient to achieve a proper correction. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Adipose TissueBlepharoplastyBlepharoptosisEyelidsAdultAgedFemaleHumansMaleMiddle AgedOculomotor MusclesRetrospective StudiesTreatment OutcomeAnatomic studyBlepharoplastyBlepharoptosisOrbital septum fatPreaponeurotic fat membrane

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.