Evidence map›Paper›PMID 41652019›Full record

ArticleEye (London, England)2026

Early vitrectomy for myopic foveoschisis before foveal detachment.

Jing-Yi Chen, Andrew S H Tsai, Wei-Hsiang Lin, Chih-Hsuan Wung, Wei-Chi Wu, Yih-Shiou Hwang, Kuan-Jen Chen, Chi-Chun Lai, Hung-Da Chou

Abstract readComparative Study
In one paragraph

Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jing-Yi ChenDepartment of Medical Education, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.ORCID 0009-0004-3676-224X
Andrew S H TsaiSingapore National Eye Centre, Singapore and DUKE NUS Medical School, Singapore, Singapore.ORCID 0000-0002-2887-3597
Wei-Hsiang LinDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
Chih-Hsuan WungDepartment of Medical Education, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
Wei-Chi WuDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.ORCID 0000-0003-3760-7255
Yih-Shiou HwangDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
Kuan-Jen ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
Chi-Chun LaiDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
Hung-Da ChouDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan. hungda.chou28@gmail.com.ORCID 0000-0002-1561-3059

Funding

Chang Gung Memorial Hospital, Linkou (Linkou Chang Gung Memorial Hospital) CMRPG5L0091
6 · The paper itself

Abstract

objectiveTo compare the surgical outcomes of myopic foveoschisis (MF) with preoperative attached versus detached fovea.

designA retrospective interventional case series.

participantsEyes with MF that underwent vitrectomy were included and were divided into an attached fovea group (26 eyes) and a detached fovea group (54 eyes).

methodsPreoperative and postoperative best-corrected visual acuity (BCVA) and optical coherence tomography were analysed. The impact of cataract and posterior vitreous detachment were also assessed.

resultsSurgical complications were low and comparable between the two groups (p = 0.830), and the BCVA was similar between the groups at postoperative 6 and 12 months. Ellipsoid zone (EZ) restoration at 6 months was significantly greater in the attached fovea group (12/26 eyes, 46%) than in the detached group (12/54 eyes, 22%; p = 0.037). A trend toward greater restoration was observed at 12 months in the attached group (15/26 [58%] versus 24/54 [44%]; p = 0.098). Eliminating the effect of cataract, the pseudophakic subgroup analyses showed only those with a baseline attached fovea had improved BCVA (p = 0.028). Furthermore, only the 55 eyes with attached posterior vitreous preoperatively showed significant BCVA improvement at 12 months (p < 0.001), whereas the 25 eyes with a preoperative detached vitreous did not (p = 0.390).

conclusionsEarly vitrectomy in MF before foveal detachment preserves outer retinal integrity and may result in better visual acuity outcomes. Future studies are needed to confirm this and should investigate the impact of posterior vitreous detachment on the outcomes.

Indexed as

Fovea CentralisMyopiaMyopia, DegenerativeRetinal DetachmentRetinoschisisVitrectomyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVisual AcuityVitreous Detachment

Identifiers

PMID41652019
PMCPMC13013932

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