SynthesisSurgical endoscopy2026
The efficacy and safety of magnetic compression anastomosis in the management of biliary obstruction: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A Common Language for Post-Transplant Anastomotic Biliary Strictures: Standardized Endoscopic Outcome Definitions and a Failure-Mode Roadmap.Medicina (Kaunas, Lithuania) · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManagement of complete biliary obstruction remains challenging when conventional endoscopic or percutaneous approaches fail. Magnetic compression anastomosis (MCA) has emerged as a minimally invasive alternative; however, the evidence base is limited and methodologically heterogeneous. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of MCA in benign and malignant biliary obstruction.
methodsOn August 27, 2025, we conducted a comprehensive search using PubMed, Scopus, Web of Science, and Cochrane Library for studies evaluating MCA in patients with biliary obstruction. The primary outcome was technical success (anastomosis creation), and secondary outcomes included recurrence rate, incidence of cholangitis, and time to anastomosis creation. Pooled single-arm estimates were calculated using a random-effects model.
resultsOf 772 articles screened, eight studies were included: 5 on benign biliary stricture (BBS) involving 102 patients, and three on malignant obstruction involving 82 patients. In the BBS group, technical success was 0.91 (95% CI: 0.84-0.95), the recurrence rate was 0.13 (95% CI: 0.034-0.38), and the incidence of cholangitis was 0.029 (95% CI: 0.01-0.087); the mean time to anastomosis creation was 9.89 days. In the malignant obstruction group, technical success was 1.00, recurrence rate was 0.073 (95% CI: 0.033-0.15), and incidence of cholangitis was 0.073 (95% CI: 0.033-0.15).
conclusionIn this systematic review and meta-analysis, MCA appears to be a feasible and safe procedure, with high technical success rates and low recurrence and cholangitis rates across both groups. Larger comparative studies and randomized controlled trials are needed to confirm these findings.
Indexed as
Identifiers
41651954What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.