Evidence map›Paper›PMID 41651661›Full record

ArticleeNeuro2026

GABA

Soraya Meftah, Max A Wilson, Jamie Elliott, Lauren McLay, Vladimirs Dobrovolskis, Samuel Rosencrans, Lewis W Taylor, Claudia Mugnaini, Rafaela Mostallino, Claire S Durrant and 1 more

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Soraya MeftahCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Max A WilsonCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Jamie ElliottCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Lauren McLayCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Vladimirs DobrovolskisCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Samuel RosencransCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Lewis W TaylorCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom.
Claudia MugnainiDip. di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena 53100, Italy.
Rafaela MostallinoDepartment of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy.
Claire S DurrantCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom sbooker@ed.ac.uk claire.durrant@ed.ac.uk.
Sam A BookerCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom sbooker@ed.ac.uk claire.durrant@ed.ac.uk.ORCID 0000-0003-1980-9873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dementia-causing diseases, including Alzheimer's disease (AD), are one of the greatest health concerns facing the aging world population. A key feature of AD is excessive accumulation of amyloid-beta, leading to synapse and cell loss in brain structures, such as the hippocampus. This neurodegeneration is preceded by impaired neuron function, notably reduced synaptic inhibition. Metabotropic GABA

Indexed as

AgingAlzheimer DiseaseCA1 Region, HippocampalPyramidal CellsReceptors, GABA-BAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalFemaleMaleMice, Inbred C57BLMice, TransgenicPresenilin-1Signal TransductionAmyloid beta-Protein PrecursorPresenilin-1Receptors, GABA-BagingAlzheimer’s diseaseamyloid pathologyGABAB receptorshippocampuspyramidal cells

Identifiers

PMID41651661
PMCPMC12880907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.