Evidence map›Paper›PMID 41651558›Full record

ArticleBMJ global health2026

Local systems, local solutions: which factors drive essential medicine availability in public health facilities across Indonesia?

Relmbuss Biljers Fanda, Ari Probandari, Yuyun Yuniar, Margo van Gurp, Wouter Guus van der Hoeven, Harimat Hendarwan, Laksono Trisnantoro, Maarten Olivier Kok

Abstract read
In one paragraph

Article in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Relmbuss Biljers FandaErasmus University Rotterdam, Rotterdam, Netherlands fanda@eshpm.eur.nl.ORCID 0000-0003-2770-4457
Ari ProbandariDepartment of Public Health, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java, Indonesia.ORCID 0000-0003-3171-5271
Yuyun YuniarResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency Republic of Indonesia, Bogor, West Java, Indonesia.
Margo van GurpKIT Royal Tropical Institute, Amsterdam, Netherlands.ORCID 0000-0001-6015-5301
Wouter Guus van der HoevenAmsterdam Public Health, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Harimat HendarwanResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency Republic of Indonesia, Bogor, West Java, Indonesia.
Laksono TrisnantoroDepartment of Health Policy and Management, Gadjah Mada University, Yogyakarta, Special Region of Yogyakarta, Indonesia.
Maarten Olivier KokErasmus University Rotterdam, Rotterdam, Netherlands.ORCID 0000-0001-8957-1253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEnsuring free access to essential medicines is a cornerstone of universal health coverage, yet many countries face persistent local disparities in medicine availability. This study investigates the factors driving variation in essential medicine availability in primary health facilities across Indonesia, focusing on the functionality of Local Pharmaceutical Systems (LOPHAS) and the influence of socioeconomic and geographical environments.

methodsEnumerators visited each of the 514 district health offices and 9831 primary health centres (PHCs) to conduct a nationwide health facility assessment. These data were combined with publicly available information on spatial, geographical, socioeconomic and health system factors. Using regression analysis, multilevel modelling and spatial autocorrelation techniques, we identified facility-level, district-level and provincial-level factors associated with the availability of 50 essential medicines in public health facilities.

resultsOn average, 66% out of 50 surveyed medicines were available in PHCs, with district-level availability ranging from 83% in top-performing areas to just 43% in the lowest. PHCs with a pharmacist, clear guidelines and proper storage infrastructure had significantly higher availability, compared with those without. Other key drivers included the application of inventory management principles (eg, First-Expired, First-Out), autonomy in procurement and district level stock levels. Spatial analysis revealed strong clustering of medicine availability within a 2 km radius (Moran's I: 0.67), with high-availability clusters present even in low-performing districts, highlighting the role of localised factors.

conclusionEssential medicine availability in Indonesian PHCs varies substantially and is closely linked to the functionality of local pharmaceutical systems. Strengthening human resources-particularly by ensuring the presence of a pharmacist in every PHC-and improving physical infrastructure are critical priorities. Beyond PHC-level interventions, targeted efforts to enhance the capacity of district health offices in managing pharmaceutical supply chains are essential, especially in rural and remote districts of eastern Indonesia.

Indexed as

Drugs, EssentialHealth Services AccessibilityPrimary Health CareHumansIndonesiaPublic Health InfrastructureSocioeconomic FactorsDrugs, EssentialHealth Services AccessibilityHealth systems evaluationInterdisciplinary ResearchPublic Health

Identifiers

PMID41651558
PMCPMC12887493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.