Evidence map›Paper›PMID 41651557›Full record

ArticleBMJ global health2026

Strengthening supply chains for pathogen genomic surveillance in Asia.

Anne-Claire Stona, Yoong Khean Khoo, La Moe, Suci Wulandari, Shreya Agoramurthy, Marya Getchell, Tze-Minn Mak, Junxiong Pang, Elyssa Jiawen Liu, Shurendar Selva Kumar and 24 more

Abstract read
In one paragraph

Article in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Anne-Claire Stona *SingHealth Duke-NUS Global Health Institute, Duke-NUS Graduate Medical School, Singapore.
Yoong Khean Khoo *SingHealth Duke-NUS Global Health Institute, Duke-NUS Graduate Medical School, Singapore khooyk@duke-nus.edu.sg.ORCID 0000-0001-7099-5566
La Moe *Centre for Outbreak Preparedness, Duke-NUS Graduate Medical School, Singapore.
Suci WulandariSingHealth Duke-NUS Global Health Institute, Duke-NUS Graduate Medical School, Singapore.
Shreya AgoramurthyCentre for Evidence and Implementation, Singapore.
Marya GetchellCentre for Outbreak Preparedness, Duke-NUS Graduate Medical School, Singapore.
Tze-Minn MakAgency for Science Technology and Research, Singapore.
Junxiong PangCentre for Outbreak Preparedness, Duke-NUS Graduate Medical School, Singapore.
Elyssa Jiawen LiuCentre for Outbreak Preparedness, Duke-NUS Graduate Medical School, Singapore.
Shurendar Selva KumarCentre for Outbreak Preparedness, Duke-NUS Graduate Medical School, Singapore.
John Cw LimSingHealth Duke-NUS Global Health Institute, Duke-NUS Graduate Medical School, Singapore.
Gavin J D SmithEmerging Infectious Diseases Programme, Duke-NUS Graduate Medical School, Singapore.
Alexandra BertholetIndependent Consultant, Washington, DC, USA.
Arika GargClinton Health Access Initiative, Boston, Massachusetts, USA.
Steven HarsonoIndependent Consultant, Singapore.
Maeve MagnerIndependent Consultant, Washington, DC, USA.
Firdausi QadriInternational Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.ORCID 0000-0002-4158-5995
Tahmina ShirinInstitute of Epidemiology Disease Control and Research Bangladesh, Dhaka, Bangladesh.
Lucia Rizka AndaluciaMinistry of Health of the Republic of Indonesia, Jakarta, Indonesia.
Syarifah Liza MuniraMinistry of Health of the Republic of Indonesia, Jakarta, Indonesia.
Phonepadith XangsayarathDepartment of Communicable Disease Control, National Center for Laboratory and Epidemiology (NCLE), Ministry of Health Lao PDR, Vientiane, Lao People's Democratic Republic.
Matthew T RobinsonLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.ORCID 0000-0003-1187-2712
Swe SetkNational Health Laboratory, Department of Medical Service, Ministry of Health Myanmar, Yangon, Myanmar.
Hlaing Myat TuDepartment of Medical Research, Ministry of Health Myanmar, Naypyitaw, Myanmar.
Govindakarnavar ArunkumarWorld Health Organisation Nepal, Kathmandu, Nepal.
Runa JhaNational Public Health Laboratory, Ministry of Health & Population, Teku, Kathmandu, Nepal.
Afreenish AmirNational Institute of Health, Islamabad, Pakistan.
Aamer IkramNational Institute of Health, Islamabad, Pakistan.
Imran NisarAga Khan University, Karachi, Pakistan.ORCID 0000-0002-2378-4720
Timothy DizonResearch Institute for Tropical Medicine, Muntinlupa, Philippines.
Cynthia SalomaUniversity of the Philippines Manila, Manila, Philippines.
Neelika Gathsaurie MalavigeDepartment of Immunology and Molecular Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Ruklanthi De AlwisEmerging Infectious Diseases Programme, Duke-NUS Graduate Medical School, Singapore.ORCID 0000-0002-2319-3701
Paul M PronykSingHealth Duke-NUS Global Health Institute, Duke-NUS Graduate Medical School, Singapore.

Funding

Gates Foundation INV-037608
6 · The paper itself

Abstract

introductionWhile pathogen genomics using next-generation sequencing (NGS) has been recommended by the WHO as an essential tool for national communicable disease surveillance programmes, procurement and supply chain management (PSM) systems for this new technology are still evolving. To assess the status of PSM systems for pathogen genomics, we examined perspectives from end-users and manufacturers across South and Southeast Asia.

methodsBetween 2022 and 2023, a cross-sectional survey was conducted among institutional partners supporting pathogen genomics among primarily low- and middle-income countries in South and Southeast Asia. This was complemented by qualitative interviews with the major regional NGS manufacturers. A PSM framework was employed to assess sales, procurement, production, distribution and post-sales support. Analyses are expressed as proportions and means or medians for continuous variables.

resultsA total of 42 partners across 13 countries, 3 genomics manufacturers and 22 laboratory personnel contributed data to this assessment. PSM challenges were reported by all countries and for all sequencing platforms. High costs of equipment and consumables were identified by 85% of respondents. Long equipment purchasing lead times and reagent re-supply times were reported by 69% and 77% of countries, respectively, with reagent resupply times averaging 8 weeks (IQR 6.2-9.0). Additional barriers included customs clearance, variability of import procedures, taxes and duties. Manufacturers reported a range of strategies to respond to PSM bottlenecks, including establishing regional hubs, distributor networks and financing schemes.

conclusionCoordinated national and regional efforts are required to improve PSM systems for pathogen genomic sequencing to enhance timely early disease detection and response capacity in South and Southeast Asia.

Indexed as

GenomicsHigh-Throughput Nucleotide SequencingPopulation SurveillanceAsiaCross-Sectional StudiesHumansGlobal HealthHealth policies and all other topicsHealth policyHealth systemsPublic Health

Identifiers

PMID41651557
PMCPMC12887454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.