Evidence map›Paper›PMID 41651550›Full record

ArticleBMJ open gastroenterology2026

Associations between patient characteristics and completeness of colon capsule endoscopy in colorectal cancer screening participants: a cross-sectional study.

Lea Østergaard Hansen, Thomas Bjørsum-Meyer, Ola Selnes, Lasse Kaalby Møller, Benedicte Schelde-Olesen, Anastasios Koulaouzidis, Gunnar Baatrup, Ulrik Deding, CareForColon2015 study group

Abstract read
In one paragraph

Article in BMJ open gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lea Østergaard HansenSurgical Research Unit, Odense University Hospital, Svendborg, Denmark lea.ostergaard.hansen@rsyd.dk.ORCID http://orcid.org/0009-0008-9188-4193
Thomas Bjørsum-MeyerSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Ola SelnesSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Lasse Kaalby MøllerSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Benedicte Schelde-OlesenSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Anastasios KoulaouzidisSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Gunnar BaatrupSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.
Ulrik DedingSurgical Research Unit, Odense University Hospital, Svendborg, Denmark.ORCID http://orcid.org/0000-0002-8263-2989
CareForColon2015 study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIncomplete investigations challenge the clinical use of colon capsule endoscopy (CCE). This results in added cost to healthcare systems and added discomfort to patients. In order to potentially lower the re-investigation rate, we aimed to investigate the association between multiple patient characteristics and complete CCE.

methodsIn 2020, the CareForColon2015 (CFC2015) Trial was initiated in the Region of Southern Denmark, investigating the performance of CCE in colorectal cancer screening. Data from the CFC2015 Trial were combined with data from multiple national registers. Completion rates were calculated and their relation to the different patient characteristics was analysed in univariate and multivariate logistic regression models.

resultsWe analysed 1472 participants, of whom 1016 (69.1%) had complete investigations. We investigated the associations between 17 patient characteristics and complete CCE investigation. The multivariate analysis showed that smokers and heavy drinkers had a higher probability of a complete investigation, with ORs of 1.69 (95% CI 1.12 to 2.55) and 2.72 (95% CI 1.52 to 4.87), respectively, compared with non-consumers. We also found that increasing income was associated with increased odds of CCE completion (OR 1.78, 95% CI 1.30 to 2.43, for the highest quartile). High body mass index (>40) and self-reported constipation or laxative use were significantly associated with incomplete CCE, with ORs of 0.40 (95% CI 0.17 to 0.97) and 0.65 (95% CI 0.47 to 0.90), respectively.

conclusionThis study tested multiple factors for association with CCE completion. The results indicate that some factors are associated with higher odds of completion, while others are associated with lower odds of completion. These results confirm that specific patient characteristics correlate with the odds of complete investigation. This can, in turn, be used to determine the individual diagnostic pathway. Additional studies are needed for less frequently reported characteristics and to further support these findings.

Indexed as

Capsule EndoscopyColonoscopyColorectal NeoplasmsEarly Detection of CancerAgedCross-Sectional StudiesDenmarkFemaleHumansLogistic ModelsMaleMass ScreeningMiddle AgedColonoscopyColorectal AdenomasColorectal Cancer ScreeningEndoscopy

Identifiers

PMID41651550
PMCPMC12887524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.