Evidence map›Paper›PMID 41650223›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A microfluidic band-pass filter for flexible fiber separation.

Zhibo Li, Clément Bielinski, Anke Lindner, Blaise Delmotte, Olivia du Roure

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhibo Li *Laboratoire de Physique et Mécanique des Milieux Hétérogènes, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris, Université Paris Sciences et Lettres, Sorbonne Université, Université Paris Cité, CNRS, Paris 75005, France.ORCID 0000-0001-5994-6421
Clément Bielinski *Laboratoire de Physique et Mécanique des Milieux Hétérogènes, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris, Université Paris Sciences et Lettres, Sorbonne Université, Université Paris Cité, CNRS, Paris 75005, France.ORCID 0000-0002-1246-4115
Anke LindnerLaboratoire de Physique et Mécanique des Milieux Hétérogènes, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris, Université Paris Sciences et Lettres, Sorbonne Université, Université Paris Cité, CNRS, Paris 75005, France.ORCID 0000-0002-5007-9568
Blaise DelmotteLaboratoire d'Hydrodynamique (LadHyX), CNRS, École Polytechnique, Institut Polytechnique de Paris, Palaiseau 91120, France.ORCID 0000-0002-9609-1175
Olivia du RoureLaboratoire de Physique et Mécanique des Milieux Hétérogènes, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris, Université Paris Sciences et Lettres, Sorbonne Université, Université Paris Cité, CNRS, Paris 75005, France.ORCID 0000-0002-6364-612X

Funding

Agence Nationale de la Recherche (ANR) ANR-10-EQPX-34Agence Nationale de la Recherche (ANR) ANR-18-IDEX-0001Agence Nationale de la Recherche (ANR) ANR-20-CE30-0006Agence Nationale de la Recherche (ANR) ANR-21-CE13-0048Agence Nationale de la Recherche (ANR) ANR-22-CE30-0024EC | European Research Council (ERC) 682367
6 · The paper itself

Abstract

The control of particle trajectories in structured microfluidic environments has significantly advanced sorting technologies, most notably through deterministic lateral displacement (DLD). While previous works have largely targeted rigid, near-spherical particles, the sorting of flexible, anisotropic objects such as fibers remains largely unexplored. Here, we combine experiments and simulations to demonstrate how tilted pillar arrays enable efficient, length-based separation of flexible fibers. We find that these arrays act as band-pass filters, selectively inducing lateral migration in fibers whose lengths are close to the array period. Fibers significantly shorter or longer exhibit small lateral deviation. This migration arises from the interplay of fluid-structure interactions between fibers and the complex flow and steric interactions with the pillars. Depending on their length, fibers exhibit distinct transport regimes: short fibers zigzag in between pillars following the flow, intermediate length fibers exhibit wrapping and jumping from one pillar to another, leading to lateral displacement, and long fibers deform extensively, following mixed zigzag-jump trajectories with small lateral migration. We identify the mechanical tension that develops in the fiber when wrapped around the pillars as the driving mechanism of cross-streamline transport. Leveraging this band-pass effect, we designed a highly efficient separation device to collect monodisperse fiber suspensions. Our findings not only expand the functional scope of DLD-like systems but also open avenues for understanding transport of anisotropic objects in porous media.

Indexed as

deterministic lateral displacementfluid-structure interactionsmicrofluidicsparticle separationporous media

Identifiers

PMID41650223
PMCPMC12890945

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.