Evidence map›Paper›PMID 41649896›Full record

ArticleQJM : monthly journal of the Association of Physicians2026

Case report: CNS tuberculoma in a patient with prior pulmonary tuberculosis.

Shreya Mehta, M Mukhyaprana Prabhu, Vivek Nayak M, Renuka Suvarna

Abstract readCase Reports
In one paragraph

Article in QJM : monthly journal of the Association of Physicians, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shreya MehtaKasturba Medical College Manipal, Manipal Academy of Higher Education, 576104, Karnataka, India.ORCID 0009-0001-8513-300X
M Mukhyaprana PrabhuKasturba Medical College Manipal, Manipal Academy of Higher Education, Department of General Medicine, 576104, Karnataka, India.
Vivek Nayak MNew York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, 11215, United States.
Renuka SuvarnaKasturba Medical College Manipal, Manipal Academy of Higher Education, Department of Endocrinology, 576104, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system (CNS) tuberculoma is a rare but severe form of tuberculosis (TB) that can mimic other neurological disorders and poses major diagnostic challenges, especially with drug resistance. We report a case of a woman in her 60s who developed CNS tuberculoma four years after completing anti-tuberculosis therapy (ATT) for pulmonary TB. She presented with progressive left-sided weakness, facial asymmetry, and dysphagia. MRI revealed a ring-enhancing lesion in the right caudate nucleus with a lipid-lactate peak on spectroscopy, consistent with tuberculoma. Drug susceptibility testing confirmed resistance to isoniazid and rifampicin, indicating multidrug-resistant TB (MDR-TB). A modified regimen with levofloxacin, ethionamide, and para-aminosalicylic acid led to neurological recovery. This case underscores the importance of considering CNS tuberculoma in patients with neurological deficits and prior TB, even after apparent cure. Early neuroimaging, drug resistance testing, and individualized therapy are vital to improving outcomes and reducing morbidity and mortality.

Indexed as

Antitubercular AgentsTuberculoma, IntracranialTuberculosis, Central Nervous SystemTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryFemaleHumansMagnetic Resonance ImagingMiddle AgedAntitubercular Agents

Identifiers

PMID41649896
PMCPMC13278773

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.