Evidence map›Paper›PMID 41649892›Full record

ArticleAnnals of medicine2026

Nomogram for predicting in-stent stenosis after pipeline embolization device treatment in patients with unruptured intracranial aneurysm: a multicenter model development and validation study.

Linggen Dong, Dachao Wei, Zizheng Wang, Qichen Peng, Xiheng Chen, Mingtao Li, Tong Li, He Liu, Ran Duan, Weitao Jin and 5 more

Abstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Linggen DongDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0002-8943-9989
Dachao WeiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0003-3389-8112
Zizheng WangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Qichen PengDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xiheng ChenDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-9837-4710
Mingtao LiDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Tong LiDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
He LiuDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Ran DuanDepartment of Neurosurgery, Peking University International Hospital, Peking University, Beijing, China.
Weitao JinDepartment of Neurosurgery, Peking University International Hospital, Peking University, Beijing, China.
Yukun ZhangDepartment of Neurosurgery, Peking University International Hospital, Peking University, Beijing, China.
Yang WangDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Yang ZhaoDepartment of Neurosurgery, Peking University International Hospital, Peking University, Beijing, China.
Ming LvDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0003-1865-2309
Peng LiuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome intracranial aneurysms (IAs) still develop in-stent stenosis (ISS) even after successful pipeline embolization device (PED) implantation. ISS increases the risk of retreatment and ischemic complications, thereby affecting the long-term prognosis of IA patients. This study aims to identify predictors for ISS after PED treatment of IAs, and develop a nomogram for assessing individual risk. MATERIALS AND

methodsThis analysis included unruptured IA patients treated with PEDs between April 2016 and October 2023 at three institutions. The patients were grouped into the training cohort and validation cohort according to the admission institution. Predictors were identified

resultsA total of 1335 IA patients were included in this study (1049 in the training cohort and 286 in the validation cohort). A total of 139 (13.3%) and 41 (14.3%) patients developed ISS in the training cohort and validation cohort, respectively. A nomogram with five predictors (difference between the proximal and distal parent artery diameters, distal stent-to-vessel diameter ratio, overlapping devices, balloon angioplasty, and dissecting aneurysms) was developed

conclusionThis nomogram showed high accuracy and clinical utility in predicting ISS after PED treatment, indicating that the nomogram can guide the identification of high-risk patients and the development of improved treatment strategies.

Indexed as

Embolization, TherapeuticIntracranial AneurysmNomogramsStentsAgedConstriction, PathologicFemaleHumansMaleMiddle AgedRetrospective StudiesROC Curvein-stent stenosisIntracranial aneurysmnomogrampipeline embolization deviceprediction model

Identifiers

PMID41649892
PMCPMC12884992

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.