ReviewScience China. Life sciences2026
Vesicles for cell crosstalk in bone: composition, function and application.
Review in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A migrasome-based osteoinductive strategy: reprogramming the bone microenvironment for accelerated coupling of angiogenesis and osteogenesis.Journal of nanobiotechnology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vesicles, with closed membrane structures containing nucleic acids, proteins, lipids, and metabolites, play a vital role in cell crosstalk. And bone, the important center of cellular information exchange, is where abundant vesicle-based cellular crosstalk occurs. This review explores the composition, functions, and clinical applications of vesicles derived from bone-related cells. Extracellular vesicles, including exosomes, microvesicles, apoptotic bodies, and newly identified structures such as migrasomes, exhibit heterogeneity in size, origin, biogenesis, and components. These vesicles facilitate complex cellular interactions, influencing bone formation, resorption, and immune responses. Extracellular vesicles hold significant promise as diagnostic biomarkers and therapeutic tools in bone-related diseases. Despite advancements, challenges remain in addressing vesicle heterogeneity, standardizing isolation techniques, and translating vesicle-based therapies into clinical practice. We summarize the latest advances in vesicle research related to bone, aiming to draw the attention of the academic community to newly identified vesicle structures, and may provide insights for studying vesicle-based interactions in other systemic organs.
Indexed as
Identifiers
41649732What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.