Evidence map›Paper›PMID 41649710›Full record

ArticleCrop health2025

drSMALL: Database for disease resistance-shaping small molecules derived from the plant microbiome.

Rui Cheng, Tingli Ke, Fangze Gui, Junnan Li, Xiaoyan Zhang, Juan Ignacio Vílchez, Haruna Matsumoto

Abstract readLetter
In one paragraph

Article in Crop health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mechanism ofFrontiers in microbiology · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui Cheng *Institute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Tingli Ke *Zhejiang Design Institute of Water Conservancy and Hydro-electric Power Co., Ltd, Hangzhou, 310002, China.
Fangze GuiInstitute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Junnan LiInstitute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Xiaoyan ZhangInstitute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Juan Ignacio VílchezInstituto de Tecnologia Química e Biológica (ITQB)-NOVA, iPlantMicro Lab. Oeiras, Lisboa, Oeiras, 2780-157, Portugal.
Haruna MatsumotoInstitute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China. mharuna@zju.edu.cn.ORCID http://orcid.org/0000-0003-0712-712X

Funding

National Key R&D Program of China 2023YFD1400901National Natural Science Foundation of China 32122074National Natural Science Foundation of China 32302291National Natural Science Foundation of China U21A20219Natural Science Foundation of Hangzhou 2024SZRZDC130001Strategic Research on 'Plant Microbiome and Agroecosystem Health'(Cao Guangbiao High Science and Technology Foundation) 2020ZL008the Fundamental Research Funds for the Central Universities 226-2024-00070
6 · The paper itself

Abstract

Recent evidence highlights the potential of the plant microbiota to increase host plant disease resistance through the production of bioactive small molecules. However, the absence of comprehensive platforms for rapid access to this information hampers progress in the field. To address this gap, we developed the Disease Resistance-Shaping Small Molecules Database (drSMALL), a freely accessible and continuously updated resource that compiles profiles of microbial small molecules, which were experimentally evidenced to be associated with host disease resistance. drSMALL interlinks detailed information on microbial species, the small molecules they produce, host plants, and targeted pathogens, facilitating streamlined access to essential data. This initiative aims to advance the understanding of small molecules in disease resistance, filling a critical gap in data accessibility while fostering deeper exploration of sustainable agricultural practices. By leveraging the natural capabilities of plant microbiomes, drSMALL seeks to support innovative strategies for enhancing crop health and resilience against diseases.

Indexed as

DatabaseDisease resistance-shapingMicrobiomePathogensSmall molecules

Identifiers

PMID41649710
PMCPMC12807323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.