ReviewJournal of gastrointestinal cancer2026
Emergence of Liquid Biopsy in Precision Oncology: A Review of its diagnostic, Predictive and Therapeutic Applications in Gallbladder Cancer.
Review in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer.Cancer reports (Hoboken, N.J.) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGallbladder cancer (GBC) is associated with a poor prognosis due to the challenges in early diagnosis. The gallbladder's anatomical constraints make it difficult to obtain tumor tissue for histological analysis and diagnostic monitoring. Consequently, liquid biopsy (LB) has emerged as a vital technique for minimally invasive extraction of tumor-derived materials. This review explores various non-invasive methods for GBC screening, with a particular focus on liquid biopsy.
methodsA comprehensive search was conducted on PubMed, Scopus, Web of Science, and Google Scholar for articles published from 1994 to 2025. The key search terms were "Gallbladder cancer", Liquid biopsy" "cfDNA", "ctDNA", "CTCs", "Exosomes" and "Clinical trial". Relevant articles on the subsections were included in this narrative literature review.
conclusionLiquid biopsy, one of the most promising and innovative diagnostic tools, was analyzed in detail, including its application in clinical studies for GBC. Despite its challenges, and varied results, this method shows potential for early GBC detection and treatment. Tissue specimens often fail to capture the dynamic evolution of cancer genomes and the genetic heterogeneity of metastatic cancers, while liquid biopsies, being more sensitive than cytology, can enhance the diagnosis and monitoring of GBC at various stages. This approach, thus, harbors the potential to facilitate cancer genetic profiling, paving the way for precision oncology strategies.
Indexed as
Identifiers
41649626What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.