Evidence map›Paper›PMID 41649516›Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2026

Over 500 000 people on kidney replacement therapy in the European Union.

Alberto Ortiz, Anneke Kramer, Vianda S Stel

Abstract readReview
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alberto OrtizDepartment of Nephrology and Hypertension, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.ORCID 0000-0002-9805-9523
Anneke KramerERA Registry, Department of Medical Informatics, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-7560-2669
Vianda S StelERA Registry, Department of Medical Informatics, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-0007-1947

Funding

Comunidad de Madrid en Biomedicina CIFRA_COR-CMComunidad de Madrid en Biomedicina P2022/BMD-7223COST CA21165European Union 101101220European Union 101137054European Union 101168626European Union HORIZON-HLTH-2023-CARE-04European Union HORIZON-MSCA-2023-DN-01-01FEDER PMP21/00109Instituto de Salud Carlos III AC22/00027Instituto de Salud Carlos III PI21/00251Instituto de Salud Carlos III PI22/00050Instituto de Salud Carlos III PI22/00469Instituto de Salud Carlos III PI25/00145Instituto de Salud Carlos III RD21/0005/0001Instituto de Salud Carlos III RD24/0004/0001
6 · The paper itself

Abstract

The burden of chronic kidney disease (CKD) is driven by mortality and the necessity of kidney replacement therapy (KRT). CKD causes one death every 20 seconds globally and is among the fastest growing causes of death. It is forecast to become the fifth most common global cause of death and the third in western Europe by 2050. It is estimated that 511 549 European Union (EU) inhabitants depend on KRT, with nearly two-thirds (≈310 000) treated by dialysis, and the remainder being kidney transplant recipients (≈200 000). KRT is provided by every EU country. France (96 317), Germany (77 900), Spain (67 604), and Italy (62 523) account for 60% of people on KRT in the EU. Prevalence per million population ranged from 560 (Luxembourg) to 2022 (Portugal). Germany (55 129) leads in the number of people on dialysis, followed by France (52 817), Italy (44 382), and Spain (29 879). In addition to differences in the relative number of dialysis and transplant patients, there were also EU-wide differences in modality of dialysis. The hemodialysis/peritoneal dialysis prevalence ratio ranged from 52.0 (Slovakia) to 3.4 (Sweden). The EU should be aware of the burden of KRT when designing regulations, such as the Accelerating Clinical Trials in the EU (ACT EU) and the EU Medical Device Regulation (MDR) or making decisions regarding the prioritization of diseases and the budget for research and healthcare.

Indexed as

Kidney Failure, ChronicRenal Replacement TherapyEuropean UnionHumansKidney TransplantationPrognosisRenal Dialysischronic kidney diseasedialysisepidemiologykidney replacement therapytransplantation

Identifiers

PMID41649516
PMCPMC13518089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.