Evidence map›Paper›PMID 41649476›Full record

ArticleSingapore medical journal2026

Case management in emergency care: insights on health-related quality of life from the Case management for At-Risk patients in the Emergency Department (CARED) programme.

Adrian Ujin Yap, Wesley Teo, Qiu Yu Tan, Colin Eng Choon Ong

Abstract read
In one paragraph

Article in Singapore medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adrian Ujin YapClinical Research Unit, JurongHealth Campus, National University Health System, Singapore.
Wesley TeoDepartment of Health Services and Outcome Research, JurongHealth Campus, National University Health System, Singapore.
Qiu Yu TanDepartment of Health Services and Outcome Research, JurongHealth Campus, National University Health System, Singapore.
Colin Eng Choon OngDepartment of Emergency Department, Ng Teng Fong General Hospital, National University Health System, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effects of emergency department (ED) transition care programmes on health-related quality of life (HRQoL) remain underexplored. This single-centre study examined the changes in HRQoL following the implementation of the Case management for At-Risk patients in the ED (CARED) programme, explored associations with frailty and identified factors linked to low HRQoL.

methodsA quasi-experimental pre-post design was employed. Participants were recruited from the ED over 6 months as part of the CARED programme. At intake, trained case managers verified demographic and medical details and conducted a comprehensive geriatric assessment incorporating the Clinical Frailty Scale (CFS; version 2.0). The EQ-5D-5L was administered at baseline and repeated 3 months post-CARED. Analyses included the chi-square test, Mann-Whitney U test, Wilcoxon signed-rank test and logistic regression (α = 0.05).

resultsThe final sample comprised 151 participants (mean age 77.4 ± 6.9 years; 75.5% female). Most (80.1%) had no-to-mild frailty, while 19.9% exhibited moderate-to-very severe frailty. Post-CARED, significant within-group improvements were observed in the overall cohort and those with no-to-mild frailty across EQ-5D-5L scores and domains ( P < 0.001), whereas improvements among individuals with greater frailty were limited. Between-group comparisons showed significantly poorer baseline and follow-up HRQoL among those with greater frailty, particularly in mobility, self-care and usual activities ( P < 0.05). Logistic regression identified male sex as the sole independent risk factor for low post-CARED EQ-5D-5L index scores (adjusted odds ratio 3.14, 95% confidence interval 1.40, 7.00).

conclusionThe CARED programme was associated with improved HRQoL, particularly among less frail individuals, while male participants had a three-fold higher likelihood of low post-intervention HRQoL.

Indexed as

Case ManagementEmergency Service, HospitalQuality of LifeAgedAged, 80 and overEmergency Room VisitsFemaleFrail ElderlyFrailtyGeriatric AssessmentHumansLogistic ModelsMaleRisk FactorsCase managementemergency departmentfrailtygeriatric assessmentquality of life

Identifiers

PMID41649476
PMCPMC13225747

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.