Evidence map›Paper›PMID 41649157›Full record

ArticleSleep2026

Mamba-based deep learning approach for sleep staging on a wireless multimodal wearable system without electroencephalography.

Andrew H Zhang, Alex He-Mo, Richard Fei Yin, Chunlin Li, Yuzhi Tang, Dharmendra Gurve, Veronique van der Horst, Aron S Buchman, Nasim Montazeri Ghahjaverestan, Maged Goubran and 2 more

Abstract read
In one paragraph

Article in Sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andrew H ZhangDepartment of Computer Science, University of Toronto, Toronto, ON, Canada.ORCID 0009-0008-2382-2425
Alex He-MoDepartment of Computer Science, University of Toronto, Toronto, ON, Canada.ORCID 0009-0007-2045-5597
Richard Fei YinDepartment of Computer Science, University of Toronto, Toronto, ON, Canada.ORCID 0009-0009-5365-700X
Chunlin LiDepartment of Computer Science, University of Toronto, Toronto, ON, Canada.
Yuzhi TangDepartment of Computer Science, University of Toronto, Toronto, ON, Canada.
Dharmendra GurveDepartment of Medicine, Sunnybrook Research Institute, Toronto, ON, Canada.
Veronique van der HorstDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Aron S BuchmanDepartment of Neurological Sciences, Rush University Medical Center, Boston, MA, United States.ORCID 0000-0002-6426-2742
Nasim Montazeri GhahjaverestanDepartment of Medicine, Sunnybrook Research Institute, Toronto, ON, Canada.
Maged GoubranDept. of Medical Biophysics, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-5880-0818
Bo WangDepartment of Computer Science, Vector Institute for Artificial Intelligence, Toronto, ON, Canada.
Andrew S P LimDept. of Medicine, University of Toronto, Toronto, ON, Canada.

Funding

Vascular and Behavioral Determinants of Superior Memory Performance from Continuous Monitoring of Everyday ActivitiesU19AG073153 · NIA · UNIVERSITY OF CHICAGO · PI GEULA, CHANGIZ, MESULAM, MAREK-MARSEL M · 2021 to 2025
$19.1M
Establishing Sleep Apnea as a non-cognitive phenotype of brainstem ADRD pathologies in older adultsR01AG071638 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ARON S BUCHMAN, Veronique VanderHorst · 2021 to 2026
$6.1M
NIA NIH HHS R01 AG071638NIA NIH HHS U19 AG073153
6 · The paper itself

Abstract

STUDY

objectivesWe investigate a Mamba-based deep learning approach for sleep staging on signals from ANNE One (Sibel Health, Chicago, IL), a non-intrusive dual-module wireless wearable system measuring chest electrocardiography, triaxial accelerometry, chest temperature, and finger photoplethysmography and finger temperature.

methodsWe obtained wearable sensor recordings from 357 adults undergoing concurrent polysomnography at a tertiary care sleep lab. Each polysomnography recording was manually scored, and these annotations served as ground truth labels for training and evaluation of our models. Polysomnography and wearable sensor data were automatically aligned using their electrocardiography channels with manual confirmation by visual inspection. We trained a Mamba-based recurrent neural network architecture on these recordings. Ensembling of model variants with similar architectures was performed.

resultsAfter ensembling, the model attains a 3-class (wake, non-rapid eye movement sleep, rapid eye movement sleep) balanced accuracy of 84.02 per cent, F1 score of 84.23 per cent, Cohen's κ of 72.89 per cent, and a Matthews correlation coefficient (MCC) score of 73.00 per cent; a 4-class (wake, light NREM [N1/N2], deep NREM [N3], REM) balanced accuracy of 75.30 per cent, F1 score of 74.10 per cent, Cohen's κ of 61.51 per cent, and MCC score of 61.95 per cent; a 5-class (wake, N1, N2, N3, REM) balanced accuracy of 65.11 per cent, F1 score of 66.15 per cent, Cohen's κ of 53.23 per cent, MCC score of 54.38 per cent.

conclusionsOur Mamba-based deep learning model can successfully infer major sleep stages from the ANNE One, a wearable system without electroencephalography, and can be applied to data from adults attending a tertiary care sleep clinic.

Indexed as

Deep LearningSleep StagesWearable Electronic DevicesWireless TechnologyAccelerometryAdultElectrocardiographyElectroencephalographyFemaleHumansMaleMiddle AgedPhotoplethysmographyPolysomnographyRecurrent Neural Networksdeep learningsleep stagingwearable devices

Identifiers

PMID41649157
PMCPMC13089490

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.