ArticleIntestinal Failure (New York, N.Y.)
Multivisceral Transplantation as curative Treatment for patients with Diffuse Splanchnic Arterial Ischemia: a case report.
Article in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Criteria for multivisceral transplantation (MVTx) have broadened. However, diffuse splanchnic arterial ischemia secondary to visceral arterial thrombosis has only been described once. Case report: A 46-year-old woman with acute-on-chronic diffuse splanchnic ischemia received a MVTx from a 14-year-old braindead donor. Cold ischemia time was 6h29, warm ischemia time 0h36. Pre-operative embolization of inferior mesenteric artery was performed and the patient was placed on continuous veno-venous hemofiltration. An aortic conduit was constructed. Non-vascularized-rectus-fascia transplantation was performed. Postoperative course was hindered by kinking of superior mesenteric artery (SMA) (requiring stenting), acute cellular rejection of intestine (early) and liver (late) (requiring high-dose solumedrol) and esophagogastric anastomotic leakage (requiring endoscopic vacuum assisted closure). At 11 months, she is alive and well. She is able to have oral intake. Conclusion: MVTx is a curative treatment for diffuse arterial splanchnic ischemia secondary to thrombosis of both the coeliac trunk and the SMA, a condition otherwise rapidly fatal.
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