Evidence map›Paper›PMID 41648858›Full record

ArticleIntestinal Failure (New York, N.Y.)

Evaluation of combined multi-chamber with compounded bags and multi-chamber bags only for British adults on home parenteral nutrition: A mixed methods pilot study.

Karen Allsopp, Simon Lal, Anne Marie Sowerbutts, Debra Jones, Michael Taylor, Simon Harrison, Arun Abraham, Kirstine Farrer, Gavin Leahy, Antje Teubner and 1 more

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In one paragraph

Article in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Karen AllsoppSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Simon LalSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Anne Marie SowerbuttsSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Debra JonesSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Michael TaylorSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Simon HarrisonSalford Care Organisation, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford, UK.
Arun AbrahamSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.
Kirstine FarrerSalford Care Organisation, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford, UK.
Gavin LeahySalford Care Organisation, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford, UK.
Antje TeubnerSalford Care Organisation, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford, UK.
Sorrel BurdenSchool of Health Sciences, University of Manchester and Manchester Academic Health Sciences Centre, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: People with chronic intestinal failure (IF) require home parenteral nutrition (HPN). Parenteral nutrition regimens can comprise of bespoke prescriptions compounded specifically for the individual, commercially produced multi-chamber bags (MCBs), or a combination of compounded and MCBs known as 'hybrid' regimens. This pilot study aimed to evaluate quality of life (QoL) and clinical outcomes with hybrid or MCBs-only parenteral nutrition regimens. Methods: This mixed-methods pilot study collected data from patients between June 2022 and January 2023. Data were gathered at baseline and 180 days post-discharge. Patients were interviewed about their lived experiences and completed a QoL questionnaire. Quantitative data were analysed using descriptive statistics while qualitative data analysis used framework analysis. Results: We recruited 28 patients, 16 on hybrid HPN regimens and 12 on MCBs. After 180 days, no catheter-related bloodstream infections were recorded. No differences were found between hybrid and MCBs-only regarding QoL. Patients on hybrid regimens reported no issues arising specifically from using two bag types, and some of those on MCBs-only appreciated extra flexibility in their lives. Conclusions: Both MCB and hybrid HPN regimens were acceptable to patients, with neither showing a substantial difference in QoL.

Indexed as

Compounded parenteral nutrition bagHome parenteral nutritionIntestinal failureMulti-chamber bagParenteral nutrition

Identifiers

PMID41648858
PMCPMC12851116

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.