Evidence map›Paper›PMID 41648822›Full record

ArticleiGIE : innovation, investigation and insights2025

Overall survival and margin status in resected gastric stromal tumors.

Fiyinfoluwa O Abraham, Tarrant McPherson, Leslie Blackshear, Yuan Liu, Theresa Gillespie, Preeyanka Sundar, Vaishali Patel, Jordan Orr, Saurabh Chawla, Steven A Keilin and 1 more

Abstract read
In one paragraph

Article in iGIE : innovation, investigation and insights, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Endoscopic intermuscular dissection of a rectal gastrointestinal stromal tumor.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fiyinfoluwa O AbrahamDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Tarrant McPhersonSchool of Public Health, Department of Biostatistics, Emory University, Atlanta, Georgia, USA.
Leslie BlackshearDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Yuan LiuSchool of Public Health, Department of Biostatistics, Emory University, Atlanta, Georgia, USA.
Theresa GillespieDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Preeyanka SundarDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Vaishali PatelDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Jordan OrrDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Saurabh ChawlaDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Steven A KeilinDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Field F WillinghamDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Studies assessing gastrointestinal stromal tumors (GISTs) have found no survival differences based on margin status; however, small sample sizes, merged anatomic locations, and limited follow-up have been limitations. This study examined the impact of margin status on overall survival in a large national cohort of patients with resected gastric GISTs. Methods: Data on patients with gastric GISTs were abstracted from the National Cancer Database, with data collected over a 16-year period (2004-2020). Exclusion criteria included the presence of other primary tumors, unknown patient/tumor characteristics, macroscopic residual margins, metastasis at diagnosis, and prior chemotherapy. The cohort was stratified according to tumor size. R0 is defined as microscopically negative margin, and R1 is microscopically positive margin. Results: After exclusions, there were 8448 patients in the analysis cohort: 8221 (97.3%) had R0 resections, and 227 (2.7%) had R1 resections. On univariate analysis, tumor size ≤5 cm ( Conclusions: Congruent with prior studies, there was no difference in survival when comparing R0 with R1 resections in gastric GIST patients without metastasis over an extended follow-up period. These data may be helpful in assessing suitability for endoscopic resection for patients with gastric GISTs.

Identifiers

PMID41648822
PMCPMC12851089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.