SynthesisFrontiers in nutrition2025
Best evidence summary for the rational use of parenteral nutrition in hospitalized cancer patients.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To systematically identify, review, and synthesize the best available evidence on the rational use of parenteral nutrition (PN) in hospitalized adult oncology patients, and to develop a practice-oriented framework encompassing decision-making, prescribing, review, compounding, administration, and monitoring, and quality management. Methods: PIPOST-based questions were developed to guide the review. Following the "5S" evidence-pyramid model, searches were performed in a top-down manner across system-level resources, guideline repositories, synthesis databases, and primary literature databases, including UpToDate, BMJ Best Practice, NICE, ESPEN, CSPEN, ASPEN, Chinese Certified Dietitian, Cochrane, JBI, PubMed, Embase, Web of Science, CINAHL, CNKI, Wanfang, and SinoMed. Eligible evidence types included clinical decision resources, clinical practice guidelines, systematic reviews and meta-analyses, expert consensus statements, and evidence summaries related to parenteral nutrition for hospitalized adult cancer patients. Study selection, quality appraisal, and data extraction were conducted independently by two trained reviewers, and any disagreements were resolved through discussion or adjudication by a third reviewer. Evidence items were regraded using the JBI pre-grading framework and synthesized thematically. The search covered all databases from their inception to 13 August 2025. Results: A total of 2,248 records were retrieved. Eighteen documents met the inclusion criteria and were included: one system-level clinical decision resource, four clinical practice guidelines, nine expert consensus statements, and four systematic reviews. From these sources, 46 discrete evidence items were distilled and organized into five domains: individualized nutritional decision-making, PN prescribing and review, PN preparation and compounding, PN administration and monitoring, safety assessment and quality management. Conclusion: Parenteral nutrition for hospitalized cancer patients should be implemented within a multidisciplinary Nutrition Support Team (NST) framework and embedded within institutional quality management systems. Structured, individualized care plans should be developed based on the best available evidence. Given variability in institutional resources, staff competencies, and evidence across tumor subgroups, key quality indicators should be specified, and routine audits should be conducted during local implementation. The ultimate goal is to improve nutritional status, clinical outcomes, and the efficiency of healthcare resource utilization among hospitalized cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.