ArticleFrontiers in nutrition2025
Optimizing clinical nutrition practices: impact of a formulary prescription-based nutrition therapy protocol in surgical patients.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Composition and influencing factors of malnutrition management costs among gastrointestinal cancer patients with chronic comorbidities.Frontiers in public health · 2026Article
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Abstract
Background: Parenteral nutrition (PN) is a crucial clinical therapy, particularly in surgical patients. However, due to the complex composition of PN formulations, the inappropriate use of PN remains widespread in clinical practice to date. This study established a formulary prescription-based nutrition therapy protocol and assessed the effectiveness of its implementation. Method: The formulary prescription-based nutrition therapy program included the development of formulary prescriptions for PN and the establishment of a perioperative nutrition medication pathway based on the formulary prescriptions. To evaluate the effect of this protocol in clinical practice, a before-and-after cohort analysis was performed to compare PN administration modalities hospital-wide and nutrition therapy strategies in targeted surgical (general surgery and thoracic surgery) departments. Patients admitted in hospital with gastrointestinal (GI) cancers and receiving abdominal surgery during the study period were further retrospectively analyzed. Nutrition status of patients was evaluated using the levels of postoperative serum albumin and prealbumin. Recovery time and surgical or nutrition-related complications and were also collated as the clinical outcomes. Results: The proportion of all-in-one (AIO) admixture orders increased from 47.2 to 85.2%, while multi-bottle systems (MBSs) decreased from 52.8 to 14.8% ( Conclusion: The formulary prescription-based nutrition therapy protocol can significantly enhance the rational use of PN drugs hospital-wide, optimize clinical nutrition strategies in the surgical patients, and improve short-term clinical outcomes in the patients undergoing GI cancer surgery.
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