Evidence map›Paper›PMID 41648650›Full record

ArticleESMO real world data and digital oncology2024

Transforming breast cancer management with real-world data and artificial intelligence.

P Heudel, B Mery, H Crochet, T Bachelot, O Tredan

Abstract read
In one paragraph

Article in ESMO real world data and digital oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P HeudelMedical Oncology Department, Centre Léon Bérard, Lyon.
B MeryMedical Oncology Department, Centre Léon Bérard, Lyon.
H CrochetHead of Data Factory, Centre Léon Bérard, Lyon, France.
T BachelotMedical Oncology Department, Centre Léon Bérard, Lyon.
O TredanMedical Oncology Department, Centre Léon Bérard, Lyon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Real-world data (RWD) provide essential insights into the effectiveness and safety of breast cancer treatments, particularly in diverse patient populations, where traditional clinical trials may have limitations. Integrating RWD into breast cancer research enhances the understanding of treatment outcomes and supports clinical decision-making, complementing the findings from controlled clinical studies. Design: This article reviews the integration of RWD into breast cancer research, highlighting the benefits and challenges. Various sources of RWD, including electronic health records (EHRs), insurance claims, and patient registries, are examined, with a focus on their application in studies of triple-negative breast cancer. The article also explores the role of artificial intelligence (AI) in managing RWD, particularly through technologies like natural language processing (NLP) and predictive analytics, which enhance data collection, storage, and analysis. Results: RWD has demonstrated significant value in informing clinical decision-making and improving patient outcomes in breast cancer treatment. The integration of AI into the management of RWD has provided deeper insights into patient outcomes and supported personalized treatment strategies. Specific studies leveraging RWD have shown improved understanding of breast cancer subtypes, such as triple-negative breast cancer, and enhanced the effectiveness of treatment protocols. Conclusion: Despite the benefits, challenges remain in integrating RWD and AI into clinical practice, particularly regarding transparency, interpretability, and ethical considerations. Addressing these challenges requires robust data governance frameworks, interdisciplinary collaboration, and investment in advanced analytical tools. The potential for RWD and AI to transform breast cancer treatment and improve patient care is significant, underscoring the need for ongoing research and collaboration.

Indexed as

artificial intelligencebig databreast cancernatural language processingreal-world datareal-world evidence

Identifiers

PMID41648650
PMCPMC12836646

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.