Evidence map›Paper›PMID 41648637›Full record

ArticlebioRxiv : the preprint server for biology2026

Type IV Secretion System Drives Lipid Mixing.

David Chetrit, Craig R Roy, Erdem Karatekin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David ChetritCellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, USA.
Craig R RoyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA.
Erdem KaratekinCellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-5934-8728

Funding

Genetic Analysis of Legionella Phagosome TraffickingR37AI041699 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2012 to 2021
$5.3M
Dynamics of membrane tension and synaptic vesicle recyclingR01NS122388 · NINDS · YALE UNIVERSITY · PI KARATEKIN, ERDEM, MACHTA, BENJAMIN BROOKS · 2021 to 2025
$2.2M
NIAID NIH HHS R37 AI041699NINDS NIH HHS R01 NS122388
6 · The paper itself

Abstract

Type IV secretion systems (T4SSs) are versatile molecular machines used by bacteria to secrete protein effectors into host cells, promoting pathogenesis, and to transfer DNA between bacteria through conjugation, driving horizontal gene transfer. Most, like Dot/Icm of the pathogen

Identifiers

PMID41648637
PMCPMC12871330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.