ArticlebioRxiv : the preprint server for biology2026
Conservation of extended sequence and structure in the branchpoint-to-3' splice site region upstream of neural microexons.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Microexons are short exons that are highly conserved in vertebrates and are essential for neurodevelopment. Their small size poses a challenge for regulatory protein binding and exon-definition splice site recognition, which typically relies on standard length exons. Here, we determine the sequence and RNA structural features of neural microexons in humans and in the chick developmental model organism. We demonstrate that a subset of neural microexons undergoes dynamic, stage-specific regulation during chick embryonic brain development that correlates with expression of known microexon regulators,
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