Evidence map›Paper›PMID 41648481›Full record

ArticlebioRxiv : the preprint server for biology2026

Structure and signaling mechanism of

Kailie Franco, Megan DiIorio, Adam J Simpkin, Ronan M Keegan, Karen Kallio, Emily Goers-Sweeney, Michelle Colbert, S James Remington, C Keith Cassidy, Arkadiusz W Kulczyk and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kailie FrancoDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA.ORCID 0000-0003-4719-225X
Megan DiIorioInstitute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.
Adam J SimpkinInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.ORCID 0000-0003-1883-9376
Ronan M KeeganInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.ORCID 0000-0002-9495-0431
Karen KallioInstitute of Molecular Biology, University of Oregon, Eugene, OR, US.
Emily Goers-SweeneyInstitute of Molecular Biology, University of Oregon, Eugene, OR, US.ORCID 0000-0002-5539-8875
Michelle ColbertInstitute of Molecular Biology, University of Oregon, Eugene, OR, US.
S James RemingtonInstitute of Molecular Biology, University of Oregon, Eugene, OR, US.
C Keith CassidyDepartment of Physics & Astronomy, University of Missouri, Columbia, MO, US.ORCID 0000-0001-8106-1187
Arkadiusz W KulczykInstitute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0001-5018-0992
Arden BaylinkDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA.ORCID 0000-0001-5522-769X

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI MARC ALLAIRE · 2017 to 2026
$28.6M
Understanding the molecular mechanisms and biological functions of a novel bleach-sensing bacterial receptor in shaping host-associated bacterial populations in response to host inflammationR00AI148587 · NIAID · WASHINGTON STATE UNIVERSITY · PI BAYLINK, ARDEN · 2022 to 2023
$498k
Understanding the molecular mechanisms and biological functions of a novel bleach-sensing bacterial receptor in shaping host-associated bacterial populations in response to host inflammationK99AI148587 · NIAID · UNIVERSITY OF OREGON · PI BAYLINK, ARDEN · 2020 to 2021
$235k
NIAID NIH HHS K99 AI148587NIAID NIH HHS R00 AI148587NIGMS NIH HHS P30 GM124169
6 · The paper itself

Abstract

Chemoreceptors, or methyl-accepting chemotaxis proteins (MCPs), are ancient and widespread prokaryotic sensors that direct taxis in response to stimuli and are attractive targets for therapeutic control of bacteria

Identifiers

PMID41648481
PMCPMC12871147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.