ArticlebioRxiv : the preprint server for biology2026
Gene function predicts divergence across molecular levels.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Genes can evolve through changes at their DNA, RNA, or protein levels. However, because these changes are measured using distinct and often incomparable metrics, their relative contributions to genic evolution remain unclear. Here, we address this challenge by developing a standardized framework for comparing evolutionary divergence in protein-coding sequences, multi-tissue expression profiles, and protein structures. Application of this approach to data from
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