Evidence map›Paper›PMID 41648380›Full record

ArticlebioRxiv : the preprint server for biology2026

A conserved

Antoine Sussfeld, Berta Vidal, Surojit Sural, Daniel M Merritt, G Robert Aguilar, Yasmin Ramadan, Oliver Hobert

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Antoine SussfeldColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Berta VidalColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Surojit SuralColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.ORCID 0000-0002-0422-9799
Daniel M MerrittColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.ORCID 0000-0001-6273-6644
G Robert AguilarColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.ORCID 0000-0001-6926-0319
Yasmin RamadanColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Oliver HobertColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.ORCID 0000-0002-7634-2854

Funding

LIM HOMEOBOX GENE LIM-6 IN MOTOR NEURON DIFFERENTIATIONR01NS039996 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Oliver Hobert · 2001 to 2026
$6.8M
Regulatory Architecture of Glia Cell Type Diversity in C. ElegansR01NS137594 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Oliver Hobert · 2024 to 2026
$1.2M
NINDS NIH HHS R01 NS039996NINDS NIH HHS R01 NS137594
6 · The paper itself

Abstract

An unusually large transcription factor arose at the base of bilaterian evolution through domain shuffling that recombined many copies of two distinct DNA binding domains, C2H2-type zinc fingers and homeodomains. The function of this deeply conserved type of protein remains poorly characterized. We describe here the complete and complex expression pattern of its sole

Identifiers

PMID41648380
PMCPMC12871285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.