Evidence map›Paper›PMID 41648351›Full record

ArticlebioRxiv : the preprint server for biology2026

The

Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Meinan Lyu, Michael E O'Donnell, Huilin Li

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Fengwei ZhengDepartment of Structural Biology, Van Andel Institute, Grand Rapids, Michigan, USA.ORCID 0000-0002-7139-4831
Nina Y YaoDNA Replication Laboratory and Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.ORCID 0000-0002-4728-6531
Roxana E GeorgescuDNA Replication Laboratory and Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.ORCID 0000-0002-1882-2358
Meinan LyuDepartment of Structural Biology, Van Andel Institute, Grand Rapids, Michigan, USA.ORCID 0000-0001-5795-0232
Michael E O'DonnellDNA Replication Laboratory and Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.ORCID 0000-0001-9002-4214
Huilin LiDepartment of Structural Biology, Van Andel Institute, Grand Rapids, Michigan, USA.ORCID 0000-0001-8085-8928

Funding

Structural mechanism of DNA replicationR35GM131754 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI Huilin Li · 2019 to 2026
$6.0M
Biochemical Mechanism and Structure of the Eukaryotic Replication ForkR01GM115809 · NIGMS · ROCKEFELLER UNIVERSITY · PI O'DONNELL, MICHAEL E · 2015 to 2022
$2.6M
Biochemistry of Eukaryotic Replication Fork and DNA RepairR35GM148159 · NIGMS · ROCKEFELLER UNIVERSITY · PI MICHAEL E O'DONNELL · 2023 to 2026
$1.7M
NIGMS NIH HHS R01 GM115809NIGMS NIH HHS R35 GM131754NIGMS NIH HHS R35 GM148159
6 · The paper itself

Abstract

DNA sliding clamps are essential for processive DNA synthesis in all domains of life and are loaded by ATP-dependent clamp loaders that recognize recessed 3' ends. How clamp loaders function at nicks and small ssDNA gaps-common intermediates during DNA repair-remains incompletely understood. Here, we show that the bacterial

Identifiers

PMID41648351
PMCPMC12871192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.