Evidence map›Paper›PMID 41648347›Full record

ArticlebioRxiv : the preprint server for biology2026

Direct binding of chromosome axis and cohesin complexes underlies meiotic chromosome architecture in fungi and plants.

Francisco Mendez Diaz, Jialu Huo, Kevin D Corbett

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francisco Mendez DiazDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla CA, USA 92093.
Jialu HuoDepartment of Molecular Biology, University of California San Diego, La Jolla CA, USA 92093.
Kevin D CorbettDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla CA, USA 92093.ORCID 0000-0001-5854-2388

Funding

Molecular mechanisms of nucleic acid recognition and maintenance in meiosis and innate immunityR35GM144121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett · 2022 to 2026
$2.7M
NIGMS NIH HHS R35 GM144121
6 · The paper itself

Abstract

In prophase of meiosis I, the proteinaceous chromosome axis provides a scaffold for the compaction of chromosomes into a linear loop array, controls the formation of interhomolog crossovers, and finally becomes integrated into the synaptonemal complex after crossovers have formed. Despite its fundamental importance, how the proteins of the meiotic chromosome axis - meiotic HORMADs, axis core proteins, and cohesin complexes - self-assemble with one another is incompletely understood. In particular, it remains unknown how cohesin complexes interact with other axis components. Here, we combine genetics in

Identifiers

PMID41648347
PMCPMC12871700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.