Evidence map›Paper›PMID 41648242›Full record

ArticlebioRxiv : the preprint server for biology2026

Amino acid variants at the P94 position in

Noah Cox-Tigre, Mia E Stewart, Jackson Tucker, Erich G Walkenhauer, Cooper S Wilce, John M Antos, Jeanine F Amacher

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Noah Cox-TigreDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.
Mia E StewartDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.ORCID 0000-0001-8798-4089
Jackson TuckerDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.
Erich G WalkenhauerDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.ORCID 0009-0002-1129-1862
Cooper S WilceDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.ORCID 0009-0005-3764-9393
John M AntosDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.ORCID 0000-0002-2555-1875
Jeanine F AmacherDepartment of Chemistry, Western Washington University, Bellingham, WA, USA.ORCID 0000-0002-3646-7521

Funding

Improved Understanding of Bacterial Sortase Activity Towards Next-Generation Protein EngineeringR15GM154315 · NIGMS · WESTERN WASHINGTON UNIVERSITY · PI AMACHER, JEANINE FAYE, ANTOS, JOHN M · 2024 to 2024
$383k
NIGMS NIH HHS R15 GM154315
6 · The paper itself

Abstract

The surface of gram-positive bacteria is a highly regulated environment with specific attachment of proteins required for viability. Sortase enzymes are cysteine transpeptidases that recognize and ligate substrates to the peptidoglycan layer in these microorganisms, which can be highly pathogenic (e.g.,

Indexed as

enzymesprotein conformational statessortase-mediated ligationsortasesspecificity

Identifiers

PMID41648242
PMCPMC12871260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.