Evidence map›Paper›PMID 41648214›Full record

ArticlebioRxiv : the preprint server for biology2026

Structural dynamics of adenine nucleotide potentiation of the human type 2 IP

Viktor Belay, Navid Paknejad, Vinay Sapuru, John D Chodera, Richard K Hite

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Viktor BelayPhysiology, Biophysics, and Systems Biology Program, Weill Cornell Medicine.
Navid PaknejadPhysiology, Biophysics, and Systems Biology Program, Weill Cornell Medicine.
Vinay SapuruPhysiology, Biophysics, and Systems Biology Program, Weill Cornell Medicine.
John D ChoderaComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center.ORCID 0000-0003-0542-119X
Richard K HiteStructural Biology Program, Memorial Sloan Kettering Cancer Center.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Pacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5M
Weill Cornell Initiative for Maximizing Student DevelopmentR25GM130494 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CARRASCO, YAZMIN PAULINA, CESARMAN, ETHEL · 2019 to 2023
$2.4M
Mechanisms of lysosomal ion transport proteins involved in pH homeostasisR01GM141553 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI HITE, RICHARD KEVIN · 2022 to 2025
$1.8M
Teaching free energy calculations to learnR35GM152017 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI John Damon Chodera · 2024 to 2026
$1.6M
Molecular Biophysics Training ProgramT32GM132081 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Olga Boudker, David Eliezer · 2020 to 2026
$1.3M
Molecular mechanisms of protein functionR35GM156616 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Richard Kevin Hite · 2025 to 2026
$1.3M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM141553NIGMS NIH HHS R24 GM154185NIGMS NIH HHS R25 GM130494NIGMS NIH HHS R35 GM152017NIGMS NIH HHS R35 GM156616NIGMS NIH HHS T32 GM132081
6 · The paper itself

Abstract

Inositol trisphosphate receptors (IP

Identifiers

PMID41648214
PMCPMC12871675

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.