Evidence map›Paper›PMID 41648108›Full record

ArticlebioRxiv : the preprint server for biology2026

Microbiota-Based Interventions Differentially Rescue Gut and Social Behavior Phenotypes in a Drosophila Autism-like Model.

Natalia A Peta Martinez, Melanie Reinoso Arnaldi, Tasha M Santiago-Rodriguez, Imilce A Rodriguez-Fernandez

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Natalia A Peta MartinezDepartment of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico, USA.ORCID 0009-0002-2085-2991
Melanie Reinoso ArnaldiDepartment of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico, USA.ORCID 0009-0007-8562-550X
Tasha M Santiago-RodriguezThe Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-2738-9784
Imilce A Rodriguez-FernandezDepartment of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico, USA.ORCID 0000-0002-5112-4834

Funding

The Role of Sensory Input to Mammalian Locomotion After the Loss of supraspinal.P20GM103642 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LASALDE-DOMINICCI, JOSE ANTONIO · 2013 to 2023
$20.6M
Research Projects CoreP30GM149367 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI JOSE Antonio LASALDE-DOMINICCI · 2023 to 2026
$5.6M
NIGMS NIH HHS P20 GM103642NIGMS NIH HHS P30 GM149367
6 · The paper itself

Abstract

Introduction: Autism spectrum disorder (ASD) is a lifelong neurological and developmental disorder that has no cure and is often accompanied by gastrointestinal (GI) issues. The bidirectional communication system known as the gut microbiota-brain axis may help explain how GI dysfunction contributes to neurological symptoms. Loss-of-function mutations in the histone demethylases Methods: Here, we evaluated multiple microbiota-based interventions, including probiotic supplementation with Results: Conclusions: Together, these findings identify

Indexed as

autism modeldrosophilaFMTgut-brain axismicrobiomeprobiotics

Identifiers

PMID41648108
PMCPMC12871106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.